SCHEMBL757647

SCHEMBL757647

C=C(C(=O)O)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
GAA P10253 1/20 0.35
HTT P42858 2/20 0.34
TSHR P16473 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
MAPK1 P28482 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
PKM P14618 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8457172 0.80 CA1 (0.52) CES2CES1
SCHEMBL9873418 0.80 TSHR (0.47) HTTTSHRLMNAMAPK1SMN1; SMN2
SCHEMBL4636359 0.79 PKM (0.34) HTTPKMSMN1; SMN2
SCHEMBL4636360 0.77 TSHR (0.33) TSHRSMN1; SMN2
SCHEMBL5553608 0.76 CES2 (0.36) CES2CES1GAAHTTLMNA
SCHEMBL31491198 0.73 CES2 (0.31) CES2CES1GAA
SCHEMBL4592243 0.71 CES2 (0.52) CES2CES1GAAHTTTSHR
SCHEMBL11699917 0.71 CYP1A2 (0.35)
SCHEMBL27970460 0.70 ALDH1A1 (0.42) CES2CES1GAAHTTTSHR
SCHEMBL27937656 0.70 MEN1 (0.40) CES2CES1GAAHTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3850018-B1 ANTIMICROBIAL CONTACT LENSES KERAMED INC (US) 2023-08-23 EP claimed
EP-3860377-B1 LIQUID SUPPLY SYSTEM FOR USE IN AEROSOL-GENERATING DEVICES PHILIP MORRIS PRODUCTS SA (CH) 2023-06-21 EP claimed
EP-3728339-B1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS AMO Ireland (IE) 2022-07-06 EP claimed
EP-3077429-B1 SOFT HYDROPHOBIC ACRYLIC MATERIALS NOVARTIS AG (CH) 2018-09-26 EP claimed
EP-1675818-B1 METHOD FOR SYNTHESIS OF ACRYLAMIDO AGMATINE GE HEALTHCARE BIO SCIENCES AB (SE) 2014-12-03 EP claimed
EP-2021388-B1 MICHAEL ADDITION ADDUCTS AS ADDITIVES FOR PAPER AND PAPERMAKING HERCULES INC (US) 2012-03-21 EP claimed
EP-1498978-B1 NONAQUEOUS ELECTROLYTIC SOLUTION AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME UBE INDUSTRIES (JP) 2010-09-08 EP claimed
EP-1287047-B1 PHOTO-POLYMERS AND USE THEREOF TERAHERTZ PHOTONICS LTD (GB) 2008-08-13 EP claimed
US-5496675-A Carrier coating and processes XEROX CORPORATION (US) 1996-03-05 US claimed
EP-4507106-A1 SEPARATOR FOR ELECTROCHEMICAL DEVICE AND ELECTROCHEMICAL DEVICE COMPRISING SAME LG Energy Solution, Ltd. (KR) 2025-02-12 EP disclosed
EP-4503302-A1 SEPARATOR FOR ELECTROCHEMICAL DEVICE AND ELECTROCHEMICAL DEVICE COMPRISING SAME LG Energy Solution Ltd. (KR) 2025-02-05 EP disclosed
US-20240413406-A1 SEPARATOR FOR ELECTROCHEMICAL DEVICE AND ELECTROCHEMICAL DEVICE INCLUDING THE SAME LG ENERGY SOLUTION, LTD. (KR) 2024-12-12 US disclosed
US-20240339724-A1 SEPARATOR FOR ELECTROCHEMICAL DEVICE AND ELECTROCHEMICAL DEVICE INCLUDING THE SAME LG ENERGY SOLUTION, LTD. (KR) 2024-10-10 US disclosed
EP-3697963-B1 METHOD FOR PRODUCING MULTIPLE PLY PAPER SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2024-06-26 EP disclosed
US-6958412-B2 Method for the preparation of pentafluorophenylacrylate polymer CHUNG-SHAN INSTITUTE OF SCIENCE & TECHNOLOGY (TW) 2005-10-25 US disclosed
US-6958412-B2 Method for the preparation of pentafluorophenylacrylate polymer CHUNG-SHAN INSTITUTE OF SCIENCE & TECHNOLOGY (TW) 2005-10-25 US disclosed
US-20050032996-A1 Method for the preparation of pentafluorophenylacrylate polymer CHUNG-SHAN INSTITUTE OF SCIENCE & TECHNOLOGY (TW) 2005-02-10 US disclosed
US-20050032996-A1 Method for the preparation of pentafluorophenylacrylate polymer CHUNG-SHAN INSTITUTE OF SCIENCE & TECHNOLOGY (TW) 2005-02-10 US disclosed
US-6566025-B1 Transfer efficiency XEROX CORPORATION 2003-05-20 US disclosed
EP-0824096-A2 Process for the preparation of halogenated (meth)acrylic esters and poly (meth) arcylates obtained with said (meth)acrylic esters Akzo Nobel N.V. (NL) 1998-02-18 EP disclosed