Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4150026 | 0.90 | LMNA (0.35) | LMNATSHRMAPTTP53HSP90AA1 | |
| SCHEMBL4636222 | 0.82 | CES2 (0.35) | LMNATSHRMAPTHTTHPGD | |
| SCHEMBL4636993 | 0.81 | CES2 (0.31) | LMNATSHRMAPTHTT | |
| SCHEMBL4636452 | 0.81 | CES2 (0.31) | LMNATSHRMAPTHTT | |
| SCHEMBL4636946 | 0.81 | RXFP1 (0.34) | LMNATSHRMAPTHTT | |
| SCHEMBL4636985 | 0.81 | RXFP1 (0.39) | MAPTHPGD | |
| SCHEMBL4145085 | 0.75 | HPGD (0.43) | LMNATSHRMAPTSMN1; SMN2POLB | |
| SCHEMBL4636499 | 0.75 | CASR (0.33) | HPGD | |
| SCHEMBL4159030 | 0.74 | TDP1 (0.45) | LMNATSHRMAPTHTTSMN1; SMN2 | |
| SCHEMBL4637560 | 0.74 | PPARG (0.34) | LMNATSHRMAPTHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937629-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007046513-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-26 | — | — | WO | disclosed |