Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.31 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4145436 | 0.91 | TDP1 (0.36) | PPARGPPARAPPARDNR1H4RAB9A | |
| SCHEMBL4636222 | 0.81 | CES2 (0.35) | RXFP1LMNAHTTMAPTTSHR | |
| SCHEMBL4636946 | 0.78 | RXFP1 (0.34) | RXFP1LMNAHTTMAPTTSHR | |
| SCHEMBL4156860 | 0.78 | LMNA (0.33) | RAB9ALMNAHTTMAPTTSHR | |
| SCHEMBL4150962 | 0.78 | TDP1 (0.37) | PPARGPPARAPPARDNR1H4RAB9A | |
| SCHEMBL4636452 | 0.77 | CES2 (0.31) | LMNAHTTMAPTTSHRMAPK1 | |
| SCHEMBL4636993 | 0.77 | CES2 (0.31) | LMNAHTTMAPTTSHRMAPK1 | |
| SCHEMBL4636985 | 0.77 | RXFP1 (0.39) | RAB9ARXFP1MAPTGAAHPGD | |
| SCHEMBL4142557 | 0.77 | RORC (0.33) | RAB9ARXFP1LMNAHTTMAPT | |
| SCHEMBL4159030 | 0.76 | TDP1 (0.45) | RAB9ALMNAHTTMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937629-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007046513-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-26 | — | — | WO | disclosed |