Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4166771 | 0.90 | RXFP1 (0.36) | RXFP1HPGDGAANPC1MAPT | |
| SCHEMBL4636946 | 0.83 | RXFP1 (0.34) | RXFP1MAPTABCB1ABCC1GPBAR1 | |
| SCHEMBL4636459 | 0.81 | LMNA (0.37) | HPGDMAPT | |
| SCHEMBL4636222 | 0.80 | CES2 (0.35) | RXFP1HPGDMAPTABCB1ABCC1 | |
| SCHEMBL4636993 | 0.80 | CES2 (0.31) | MAPTGPBAR1 | |
| SCHEMBL4636452 | 0.80 | CES2 (0.31) | MAPTGPBAR1 | |
| SCHEMBL4637560 | 0.77 | PPARG (0.34) | RXFP1HPGDGAAMAPTRAB9A | |
| SCHEMBL4157346 | 0.76 | HPGD (0.47) | HPGDGAANPC1RAB9AMEN1 | |
| SCHEMBL4150006 | 0.75 | MEN1 (0.43) | HPGDGAAMAPTMEN1KMT2A | |
| SCHEMBL4159030 | 0.75 | TDP1 (0.45) | HPGDGAAMAPTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937629-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007046513-A2 | BENZOYLUREA COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-26 | — | — | WO | disclosed |