SCHEMBL46366

SCHEMBL46366

OC1CCC2(CC1)OCCO2

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
KDM4E B2RXH2 1/20 0.33
TP53 P04637 1/20 0.33
POLB P06746 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ESR2 Q92731 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.32
ALDH1A1 P00352 2/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31569967 0.90 TSHR (0.36) TSHR
SCHEMBL20869261 0.87 TSHR (0.42) LMNATSHRALDH1A1HPGD
SCHEMBL17459562 0.85 LMNA (0.32) LMNAL3MBTL1MAPK1ALDH1A1HPGD
SCHEMBL19339207 0.85 LMNA (0.32) LMNAL3MBTL1MAPK1ALDH1A1HPGD
SCHEMBL17468591 0.85 LMNA (0.32) LMNAL3MBTL1MAPK1ALDH1A1HPGD
SCHEMBL12222390 0.85 LMNA (0.32) LMNAL3MBTL1MAPK1ALDH1A1HPGD
SCHEMBL1338928 0.84 KDM4E (0.31) LMNAL3MBTL1KDM4ETP53POLB
SCHEMBL20859051 0.82 TSHR (0.48) LMNAL3MBTL1KDM4ETP53POLB
SCHEMBL22995757 0.80 TSHR (0.46) LMNATSHRALDH1A1HPGD
SCHEMBL19309616 0.80 TSHR (0.46) TSHRALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1431 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250230136-A1 METHOD FOR PRODUCING KETONES BAYER AKTIENGESELLSCHAFT (DE) 2025-07-17 US claimed
CN-118891253-A Process for preparing ketones 拜耳公司 2024-11-01 CN claimed
WO-2023180162-A1 METHOD FOR PRODUCING KETONES BAYER AKTIENGESELLSCHAFT (DE) 2023-09-28 WO claimed
EP-4355748-B1 SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION SANOFI SA (FR) 2026-05-13 EP disclosed
EP-4212523-B1 PYRAZOLE AMIDE COMPOUNDS AS IRAK INHIBITORS RIGEL PHARMACEUTICALS INC (US) 2026-05-06 EP disclosed
EP-3870583-B1 SUBSTITUTED INDOLE AND INDAZOLE COMPOUNDS BRISTOL MYERS SQUIBB CO (US) 2026-04-22 EP disclosed
EP-4727940-A1 DIHYDROPYRIMIDINE-2, 4 (1H, 3H) -DIONE-CONTAINING POLYCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREOF AND USE THEREOF Linkcure Therapeutics (KY) 2026-04-22 EP disclosed
US-12606568-B2 SMARCA degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2026-04-21 US disclosed
US-12595253-B2 Benzamides of pyrazolylamino-pyrimidinyl derivatives, and compositions and methods thereof LYNK PHARMACEUTICALS CO. LTD. (CN) 2026-04-07 US disclosed
US-20260092071-A1 COMPOUNDS AND COMPOSITIONS AS SMARCA2/4 DEGRADERS AND USES THEREOF UNIV MICHIGAN (US) 2026-04-02 US disclosed
US-20260085064-A1 SUBSTITUTED BENZOFURANYL AND BENZOXAZOLYL COMPOUNDS AND USES THEREOF KARYOPHARM THERAPEUTICS INC (US) 2026-03-26 US disclosed
EP-0719259-A1 SUBSTITUTED PYRIDINES AND PYRIMIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES Hoechst Schering AgrEvo GmbH (DE) 1996-07-03 EP disclosed
WO-1995031441-A1 HETEROCYCLYLAMINO- AND HETEROCYCLYLOXY-CYCLOALKYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PESTICIDES AND FUNGICIDES HOECHST SCHERING AGREVO GMBH (DE) 1995-11-23 WO disclosed
WO-1995007894-A1 SUBSTITUTED PYRIDINES AND PYRIMIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES HOECHST SCHERING AGREVO GMBH (DE) 1995-03-23 WO disclosed
EP-0317332-B1 SULFONANILIDE COMPOUNDS TAISHO PHARMACEUTICAL CO. LTD (JP) 1993-05-19 EP disclosed
US-4885367-A ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS; SIDE EFFECT REDUCTION TAISHO PHARMACEUTICAL CO., LTD. (JP) 1989-12-05 US disclosed
EP-0317332-A2 Sulfonanilide compounds TAISHO PHARMACEUTICAL CO. LTD (JP) 1989-05-24 EP disclosed
US-4466977-A N-[2-Amino(oxy- or thia- group-substituted-cycloaliphatic)]benzeneacetamides and -benzamide analgesics THE UPJOHN COMPANY (US) 1984-08-21 US disclosed
EP-0108602-A1 N-(2-aminocycloalkyl)benzamide and benzeneacetamide derivatives THE UPJOHN COMPANY (US) 1984-05-16 EP disclosed
US-4360531-A Substituted cycloalkanes THE UPJOHN COMPANY (US) 1982-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595253-B2 Benzamides of pyrazolylamino-pyrimidinyl derivatives, and compositions and methods thereof JAK1, JAK3, JAK2 LMNA 3046/4885L3MBTL1 3609/4885KDM4E 2018/4885
US-12606568-B2 SMARCA degraders and uses thereof SMARCA1, SMARCD1, SMARCC1 LMNA 793/4885L3MBTL1 2778/4885KDM4E 518/4885
US-20250230136-A1 METHOD FOR PRODUCING KETONES PC, BCKDK, HOGA1 LMNA 1381/4885L3MBTL1 4672/4885KDM4E 1411/4885
US-20260092071-A1 COMPOUNDS AND COMPOSITIONS AS SMARCA2/4 DEGRADERS AND USES THEREOF SMARCC2, SMARCC1, SMARCA2 LMNA 582/4885L3MBTL1 3719/4885KDM4E 1118/4885
US-20260085064-A1 SUBSTITUTED BENZOFURANYL AND BENZOXAZOLYL COMPOUNDS AND USES THEREOF BCL6, MALT1, BCL6B LMNA 1171/4885L3MBTL1 3498/4885KDM4E 834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.