Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 7/20 | 0.53 |
| ▸ | IGF2R | P11717 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GJA1 | P17302 | 1/20 | 0.45 |
| ▸ | GJB2 | P29033 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FGF1 | P05230 | 1/20 | 0.42 |
| ▸ | FGF2 | P09038 | 1/20 | 0.42 |
| ▸ | VEGFA | P15692 | 1/20 | 0.42 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15518255 | 0.88 | LGALS8 (0.56) | LGALS8IGF2RMEN1KMT2AGJA1 | |
| SCHEMBL27494277 | 0.85 | IGF2R (0.44) | LGALS8IGF2RMEN1KMT2AGJA1 | |
| SCHEMBL4103172 | 0.84 | LGALS8 (0.52) | LGALS8IGF2RMEN1KMT2AGJA1 | |
| SCHEMBL28635537 | 0.83 | LGALS8 (0.44) | LGALS8IGF2RMEN1KMT2AGJA1 | |
| SCHEMBL1984503 | 0.82 | LGALS8 (0.52) | LGALS8IGF2RMEN1KMT2APTPN1 | |
| SCHEMBL4178440 | 0.82 | KDM4E (0.56) | LGALS8IGF2RMEN1KMT2AGJB2 | |
| Trehalose SCHEMBL4636635 | 0.82 | IGF2R (0.56) | IGF2RMEN1KMT2AGJA1GJB2 | |
| SCHEMBL19958457 | 0.81 | TLR4 (0.50) | IGF2RMEN1KMT2AGJA1GJB2 | |
| SCHEMBL4410620 | 0.80 | MEN1 (0.58) | LGALS8IGF2RMEN1KMT2AGJA1 | |
| SCHEMBL7567716 | 0.80 | MEN1 (0.54) | LGALS8MEN1KMT2AGJA1GJB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931306-A1 | NON-PROTEIN STABILIZED CLOSTRIDIAL TOXIN PHARMACEUTICAL COMPOSITIONS | Allergan, Inc. (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007041664-A1 | NON-PROTEIN STABILIZED CLOSTRIDIAL TOXIN PHARMACEUTICAL COMPOSITIONS | ALLERGAN, INC. (US) | 2007-04-12 | — | — | WO | disclosed |
| WO-2005089503-A2 | CD4-IGG2 FORMULATIONS | PROGENICS PHARMACEUTICALS, INC. (US) | 2005-09-29 | — | — | WO | disclosed |
| WO-2004084816-A2 | IMPROVED CD4-IgG2 FORMULATIONS | PROGENICS PHARMACEUTICALS, INC. (US) | 2004-10-07 | — | — | WO | disclosed |