Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL439363 | 0.82 | MC4R (0.51) | MTNR1AMTNR1BNPC1PKMEPHX2 | |
| Hydrochloric Acid SCHEMBL439362 | 0.82 | MC4R (0.51) | MTNR1AMTNR1BNPC1PKMEPHX2 | |
| SCHEMBL440735 | 0.79 | PKM (0.45) | NPC1PKMEPHX2RAB9ASMN1; SMN2 | |
| SCHEMBL440734 | 0.79 | PKM (0.45) | NPC1PKMEPHX2RAB9ASMN1; SMN2 | |
| SCHEMBL18428493 | 0.77 | HTR2A (0.56) | ALDH1A1HTR2AKMT2AHTR2CHTR2B | |
| SCHEMBL324342 | 0.77 | HTR2A (0.56) | ALDH1A1HTR2AKMT2AHTR2CHTR2B | |
| Bicarbonate SCHEMBL11468689 | 0.75 | HTR2A (0.54) | ALDH1A1HTR2AKMT2AHTR2CHTR2B | |
| SCHEMBL10184513 | 0.73 | DGAT1 (0.49) | NPC1RAB9AALDH1A1LMNAKMT2A | |
| SCHEMBL3189768 | 0.73 | SMN1; SMN2 (0.61) | MTNR1AMTNR1BNPC1PKMEPHX2 | |
| SCHEMBL28002154 | 0.72 | MGLL (0.51) | ALDH1A1HTR2AKMT2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | DGAT2, DGAT1, DLAT | MTNR1A 1862/4885MTNR1B 1684/4885NPC1 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.