Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16825800 | 0.84 | MEN1 (0.46) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL654290 | 0.80 | ADRB1 (0.43) | SLC6A4SLC6A2OPRD1OPRM1KDM4E | |
| SCHEMBL656548 | 0.80 | KDM4E (0.48) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL654110 | 0.78 | ADRB1 (0.49) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL654281 | 0.78 | CYP2D6 (0.49) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL656574 | 0.78 | P4HB (0.39) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL653052 | 0.78 | MMP2 (0.39) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL652763 | 0.78 | SLC6A2 (0.41) | SIGMAR1SLC6A4SLC6A2KCNH2HTR1A | |
| Hydrochloric Acid SCHEMBL16825663 | 0.77 | CYP2D6 (0.47) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL653788 | 0.77 | OPRD1 (0.51) | OPRD1OPRM1KCNH2HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492534-B1 | CARBAMIC ACID COMPOUNDS COMPRISING A PIPERAZINE LINKAGE AS HDAC INHIBITORS | TOPOTARGET UK LTD (GB) | 2008-06-25 | — | — | EP | disclosed |