Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108260 | 0.90 | ALDH1A1 (0.42) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL3115134 | 0.81 | KDM4E (0.40) | ALDH1A1BRD4KDM4EMEN1KMT2A | |
| SCHEMBL15058572 | 0.79 | ALDH1A1 (0.38) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL5550162 | 0.77 | ALDH1A1 (0.36) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL6258436 | 0.75 | ALDH1A1 (0.38) | ALDH1A1BRD4KDM4EPOLBMEN1 | |
| SCHEMBL15058573 | 0.74 | CTSL (0.31) | ALDH1A1CTSLCTSSCTSK | |
| SCHEMBL11118508 | 0.73 | KDR (0.45) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL31472460 | 0.73 | ALDH1A1 (0.45) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL9255856 | 0.72 | ALDH1A1 (0.53) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL8284428 | 0.70 | HPGD (0.58) | ALDH1A1BRD4CYP3A4KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1629824-B1 | New coupler components | HENKEL KGAA (DE) | 2008-04-30 | — | — | EP | claimed |
| US-7211119-B2 | Coupling components | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2007-05-01 | — | — | US | claimed |
| EP-1629824-B1 | New coupler components | HENKEL KGAA (DE) | 2008-04-30 | — | — | EP | disclosed |
| US-7211119-B2 | Coupling components | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2007-05-01 | — | — | US | disclosed |
| EP-1629824-A1 | New coupler components | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-03-01 | — | — | EP | disclosed |
| US-20060000032-A1 | Novel coupling components | HENKEL AG & CO. KGAA (DE) | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060000032-A1 | Novel coupling components | KRT18, C9, H1-4 | ALDH1A1 450/4885CASP3 2248/4885SENP8 4651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.