Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.36 |
| ▸ | STK16 | O75716 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | DMPK | Q09013 | 1/20 | 0.36 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108260 | 0.90 | ALDH1A1 (0.42) | KDM4EBRD4GLAALDH1A1CTSL | |
| SCHEMBL4637282 | 0.81 | ALDH1A1 (0.51) | KDM4EBRD4ALDH1A1CTSLCTSS | |
| SCHEMBL11707894 | 0.79 | KDM4E (0.49) | KDM4EBRD4GLAALDH1A1KMT2A | |
| SCHEMBL15058572 | 0.78 | ALDH1A1 (0.38) | KDM4EBRD4GLAALDH1A1CTSL | |
| SCHEMBL34077 | 0.77 | KDM4E (0.50) | KDM4EBRD4GLAALDH1A1KMT2A | |
| SCHEMBL5550162 | 0.77 | ALDH1A1 (0.36) | KDM4EBRD4GLAALDH1A1CTSL | |
| SCHEMBL5692217 | 0.76 | KDM4E (0.54) | KDM4EBRD4GLAALDH1A1KMT2A | |
| SCHEMBL6258436 | 0.75 | ALDH1A1 (0.38) | KDM4EBRD4GLAALDH1A1KMT2A | |
| SCHEMBL109784 | 0.74 | ALDH1A1 (0.47) | KDM4EBRD4GLAALDH1A1KMT2A | |
| SCHEMBL5176527 | 0.74 | KDM4E (0.41) | KDM4EBRD4GLAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9445977-B2 | Multi-tonal one step dyeing | HENKEL AG & CO. KGAA (DE) | 2016-09-20 | — | — | US | disclosed |
| US-9402795-B2 | Multi-tonal one-step dyes | HENKEL AG & CO. KGAA (DE) | 2016-08-02 | — | — | US | disclosed |
| US-20160158582-A1 | PRODUCTS IN DISPENSER FOR OXIDATIVE CHANGE TO COLOUR OF KERATINOUS FIBRES | HENKEL AG & CO. KGAA (DE) | 2016-06-09 | — | — | US | disclosed |
| US-20150366772-A1 | MULTI-TONAL ONE-STEP DYES | HENKEL AG & CO. KGAA (DE) | 2015-12-24 | — | — | US | disclosed |
| US-20150366773-A1 | MULTI-TONAL ONE STEP DYEING | HENKEL AG & CO. KGAA (DE) | 2015-12-24 | — | — | US | disclosed |
| US-7678156-B2 | Compositions for treating keratinic fibers, methods of treating such fibers therewith and compounds contained therein | HENKEL AG & CO. KGAA (DE) | 2010-03-16 | — | — | US | disclosed |
| US-20070287686-A1 | Substance for Dyeing Keratinic Fibers | HENKEL KGAA (DE) | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287686-A1 | Substance for Dyeing Keratinic Fibers | KRT18, SCNN1B, COL1A1 | KDM4E 615/4885BRD4 308/4885GLA 847/4885 |
| US-20160158582-A1 | PRODUCTS IN DISPENSER FOR OXIDATIVE CHANGE TO COLOUR OF KERATINOUS FIBRES | KRT18, MARK4, NOX4 | KDM4E 944/4885BRD4 2005/4885GLA 922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.