Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.31 |
| ▸ | ABAT | P80404 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Vinylphenol SCHEMBL4451038 | 0.94 | ALDH1A1 (0.37) | ALDH1A1KMT2ATDP1GAA | |
| Styrene SCHEMBL10605079 | 0.83 | ALDH1A1 (0.50) | ALDH1A1 | |
| Chavicol SCHEMBL4605750 | 0.80 | XDH (0.38) | ALDH1A1KMT2AMAPTGAAKDM4E | |
| Styrene SCHEMBL11156150 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KMT2AMAPTSMN1; SMN2 | |
| 4-Vinylphenol SCHEMBL28351880 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KMT2AALDH5A1ABATCYP2C9 | |
| 4-Vinylphenol SCHEMBL28398600 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KMT2AALDH5A1ABATCYP2C9 | |
| Phenol SCHEMBL2420081 | 0.77 | CA12 (0.44) | KMT2ATDP1 | |
| Phenol SCHEMBL6858847 | 0.77 | CA12 (0.44) | KMT2ATDP1 | |
| Phenol SCHEMBL9243036 | 0.77 | CA12 (0.44) | KMT2ATDP1 | |
| Phenol SCHEMBL4636947 | 0.76 | TRPA1 (0.33) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101331172-A | Polyarylate-siloxane copolymers | MOMENTIVE PERFORMANCE MAT INC (US) | 2008-12-24 | — | — | CN | claimed |
| CN-101258158-A | Siloxane bischloroformates | GEN ELECTRIC (US) | 2008-09-03 | — | — | CN | claimed |
| CN-101331172-A | Polyarylate-siloxane copolymers | MOMENTIVE PERFORMANCE MAT INC (US) | 2008-12-24 | — | — | CN | disclosed |
| CN-101258158-A | Siloxane bischloroformates | GEN ELECTRIC (US) | 2008-09-03 | — | — | CN | disclosed |
| EP-1937693-A1 | SILOXANE BISCHLOROFORMATES | General Electric Company (US) | 2008-07-02 | — | — | EP | disclosed |
| CN-1324071-C | Siloxane bischloroformates | GEN ELECTRIC (US) | 2007-07-04 | — | — | CN | disclosed |
| US-20070093629-A1 | Siloxane bishchloroformates | GENERAL ELECTRIC COMPANY (US) | 2007-04-26 | — | — | US | disclosed |
| WO-2007037888-A1 | SILOXANE BISCHLOROFORMATES | GENERAL ELECTRIC COMPANY (US) | 2007-04-05 | — | — | WO | disclosed |
| CN-1688634-A | Siloxane bischloroformates | GEN ELECTRIC (US) | 2005-10-26 | — | — | CN | disclosed |