Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | BAX | Q07812 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL2420081 | 1.00 | CA12 (0.44) | CA12CA1CA2GLACA3 | |
| Phenol SCHEMBL9243036 | 1.00 | CA12 (0.44) | CA12CA1CA2GLACA3 | |
| 4-Vinylphenol SCHEMBL4451038 | 0.86 | ALDH1A1 (0.37) | CA12CA1CA2GLACA3 | |
| Biphenyl SCHEMBL121313 | 0.83 | ALDH1A1 (0.39) | TDP1MMP3BCL2L1MEN1NPC1 | |
| Biphenyl SCHEMBL14358032 | 0.83 | ALDH1A1 (0.39) | TDP1MMP3BCL2L1MEN1NPC1 | |
| Phenol SCHEMBL4636947 | 0.83 | TRPA1 (0.33) | CA12CA1CA2GLACA3 | |
| Chavicol SCHEMBL4444832 | 0.82 | XDH (0.34) | MEN1KMT2A | |
| Biphenyl SCHEMBL8599004 | 0.82 | ALDH1A1 (0.38) | TDP1MMP3BCL2L1MEN1KMT2A | |
| SCHEMBL8928683 | 0.81 | MMP3 (0.39) | TDP1MMP3BCL2L1ESR1ESR2 | |
| 2-Allylphenol SCHEMBL4453152 | 0.81 | GABRA1 (0.36) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6780956-B2 | FOR CONTROLLING PHYSICAL PROPERTIES OF POLYCARBONATESILOXANE COPOLYMERS; FOR PRODUCTION OF OPTICAL DISKS | GENERAL ELECTRIC COMPANY | 2004-08-24 | — | — | US | disclosed |
| US-20030065122-A1 | Method of making silicone copolycarbonates having random and blocky substructures | GENERAL ELECTRIC COMPANY | 2003-04-03 | — | — | US | disclosed |