Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 7/20 | 0.34 |
| ▸ | NPY1R | P25929 | 5/20 | 0.34 |
| ▸ | NPY2R | P49146 | 3/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13865707 | 1.00 | MEN1 (0.42) | MEN1CYP1A2KMT2ASMN1; SMN2OPRM1 | |
| SCHEMBL20969045 | 1.00 | MEN1 (0.42) | MEN1CYP1A2KMT2ASMN1; SMN2OPRM1 | |
| SCHEMBL11418945 | 0.94 | MEN1 (0.46) | MEN1CYP1A2KMT2ASMN1; SMN2OPRM1 | |
| SCHEMBL17525175 | 0.94 | MEN1 (0.46) | MEN1CYP1A2KMT2ASMN1; SMN2OPRM1 | |
| SCHEMBL434308 | 0.92 | MEN1 (0.48) | MEN1CYP1A2KMT2ASMN1; SMN2OPRM1 | |
| SCHEMBL15925196 | 0.86 | — | — | |
| SCHEMBL26020020 | 0.86 | — | — | |
| SCHEMBL7935092 | 0.84 | MEN1 (0.44) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL12664131 | 0.83 | MEN1 (0.40) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL17030187 | 0.83 | MEN1 (0.42) | MEN1CYP1A2KMT2ASMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081363-A1 | COMPOSITION COMPRISING A FIRST RAS INHIBITOR, SECOND RAS INHIBITOR AND A SHP2 INHIBITOR FOR USE IN THE TREATMENT OF CANCER | Revolution Medicines, Inc. (US) | 2024-04-18 | — | — | WO | disclosed |
| US-20230312599-A1 | ALDOSE REDUCTASE INHIBITORS AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2023-10-05 | — | — | US | disclosed |
| EP-4183774-A1 | SULFONYLUREA DERIVATIVE AND MEDICAL USES THEREOF | Shanghai Senhui Medicine Co., Ltd. (CN) | 2023-05-24 | — | — | EP | disclosed |
| EP-3079015-B1 | PHOTOMASK BLANK, RESIST PATTERN FORMING PROCESS, AND METHOD FOR MAKING PHOTOMASK | SHINETSU CHEMICAL CO (JP) | 2020-04-29 | — | — | EP | disclosed |
| EP-3233844-B1 | 3-(6-ALKOXY-5-CHLOROBENZO[D]ISOXAZOL-3-YL)PROPANOIC ACID USEFUL AS KYNURENINE MONOOXYGENASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2019-05-15 | — | — | EP | disclosed |
| US-8871252-B2 | pH-responsive liposome | NANOTHETA CO, LTD. (JP) | 2014-10-28 | — | — | US | disclosed |
| US-8871883-B2 | Biocompatible coating for implantable medical devices | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2014-10-28 | — | — | US | disclosed |
| US-20140228435-A1 | COMPOSITION AND METHOD OF SYNTHESIZING A BIOMOLECULE AND ITS THERAPEUTICS APPLICATIONS | BAKHTIARI MEHDI (IR) | 2014-08-14 | — | — | US | disclosed |
| US-8222255-B2 | Antifungal agents | MERCK SHARP & DOHME CORP. (US) | 2012-07-17 | — | — | US | disclosed |
| US-20120064148-A1 | PH-RESPONSIVE LIPOSOME | BIONANOSHEETER CO., LTD. (JP) | 2012-03-15 | — | — | US | disclosed |
| EP-2407158-A1 | PH-RESPONSIVE LIPOSOME | Bionanosheeter Co., Ltd. (JP) | 2012-01-18 | — | — | EP | disclosed |
| US-20110172225-A1 | ANTIFUNGAL AGENTS | MERCK SHARP & DOHME CORP. (US) | 2011-07-14 | — | — | US | disclosed |
| US-7838685-B2 | novel complex lipid having a cationic functional group derived from an amino acid; useful as a component of a stable, safe and functional carrier of a substance having an efficacy in pharmaceutical drugs, reagents, cosmetics and the like | Takeoka, Shinji (JP) | 2010-11-23 | — | — | US | disclosed |
| US-7838685-B2 | novel complex lipid having a cationic functional group derived from an amino acid; useful as a component of a stable, safe and functional carrier of a substance having an efficacy in pharmaceutical drugs, reagents, cosmetics and the like | Takeoka, Shinji (JP) | 2010-11-23 | — | — | US | disclosed |
| US-20100292426-A1 | BIOCOMPATIBLE COATING FOR IMPLANTABLE MEDICAL DEVICES | HOSSAINY SYED F A | 2010-11-18 | — | — | US | disclosed |
| US-7776926-B1 | Blend of a biologically compatible structural component such as an acrylic ester (co)polymer, and a copolymer having a biobeneficial or bioactive moiety, such as a block copolymer of polyethylene glycol and a polyacrylate; coating medical devices such as stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2010-08-17 | — | — | US | disclosed |
| US-20100121105-A1 | Composition and Method of synthesizing a biomolecule and its therapeutics applications | BAKHTIARI MEHDI | 2010-05-13 | — | — | US | disclosed |
| WO-2009045311-A1 | ANTIFUNGAL AGENTS | MERCK & CO., INC. (US) | 2009-04-09 | — | — | WO | disclosed |
| US-20090012306-A1 | Cationic Amino Acid Type Lipid | Takeoka, Shinji (JP) | 2009-01-08 | — | — | US | disclosed |
| US-20090012306-A1 | Cationic Amino Acid Type Lipid | Takeoka, Shinji (JP) | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140228435-A1 | COMPOSITION AND METHOD OF SYNTHESIZING A BIOMOLECULE AND ITS THERAPEUTICS APPLICATIONS | PRKCZ, PRKCH, PRKCD | MEN1 1128/4885CYP1A2 4230/4885KMT2A 2480/4885 |
| US-20120064148-A1 | PH-RESPONSIVE LIPOSOME | LIPA, SMPD3, SMPD1 | MEN1 652/4885CYP1A2 4841/4885KMT2A 2691/4885 |
| US-20110172225-A1 | ANTIFUNGAL AGENTS | GMDS, GBA3, UGGT1 | MEN1 730/4885CYP1A2 567/4885KMT2A 4695/4885 |
| US-20230312599-A1 | ALDOSE REDUCTASE INHIBITORS AND METHODS OF USE THEREOF | ALDOA, AKR1B1, AKR1C2 | MEN1 4369/4885CYP1A2 1273/4885KMT2A 4110/4885 |
| US-20090012306-A1 | Cationic Amino Acid Type Lipid | SLC7A1, NCEH1, DAO | MEN1 2776/4885CYP1A2 2136/4885KMT2A 1536/4885 |
| US-20100121105-A1 | Composition and Method of synthesizing a biomolecule and its therapeutics applications | GHRHR, GHSR, IGF1R | MEN1 774/4885CYP1A2 4308/4885KMT2A 2659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.