Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12050287 | 0.78 | THRB (0.63) | THRBALDH1A1LMNATSHRMEN1 | |
| SCHEMBL11973892 | 0.77 | THRB (0.65) | THRBALDH1A1LMNATSHRMEN1 | |
| SCHEMBL463967 | 0.76 | ALDH1A1 (0.58) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL5410713 | 0.74 | MCOLN3 (0.78) | ALDH1A1LMNAMEN1KMT2APOLB | |
| SCHEMBL27826914 | 0.74 | MCOLN3 (0.55) | ALDH1A1LMNATDP1POLBMCOLN3 | |
| SCHEMBL27826958 | 0.74 | MCOLN3 (0.72) | ALDH1A1LMNAMEN1KMT2ATDP1 | |
| SCHEMBL15881314 | 0.73 | HPGD (0.54) | THRBALDH1A1LMNATSHRMEN1 | |
| SCHEMBL16296992 | 0.71 | THRB (0.51) | THRBALDH1A1LMNATSHRMEN1 | |
| SCHEMBL16296830 | 0.71 | THRB (0.51) | THRBALDH1A1LMNATSHRMEN1 | |
| SCHEMBL16097913 | 0.71 | KMT2A (0.72) | THRBALDH1A1LMNATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120064062-A1 | INHIBITORS OF BACTERIAL PLASMINOGEN ACTIVATORS | MICROBIOTIX, INC. | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120064062-A1 | INHIBITORS OF BACTERIAL PLASMINOGEN ACTIVATORS | PLG, PLAU, TFPI | THRB 2609/4885ALDH1A1 4200/4885LMNA 1650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.