Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | BRAF | P15056 | 1/20 | 0.54 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.51 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594332 | 0.85 | ALDH1A1 (0.71) | ALDH1A1NPC1GAAMCOLN3LMNA | |
| SCHEMBL9931486 | 0.80 | CCR2 (0.70) | LMNAMEN1KMT2ABRAFPKM | |
| SCHEMBL16296678 | 0.78 | MAPT (0.57) | ALDH1A1NPC1LMNAMEN1KMT2A | |
| SCHEMBL7569883 | 0.78 | PKM (0.79) | ALDH1A1NPC1GAAMCOLN3LMNA | |
| SCHEMBL7578803 | 0.78 | TP53 (0.73) | ALDH1A1NPC1GAAMCOLN3MEN1 | |
| SCHEMBL15009888 | 0.78 | ALDH1A1 (0.61) | ALDH1A1NPC1GAAMCOLN3LMNA | |
| SCHEMBL10878905 | 0.78 | ALDH1A1 (0.61) | ALDH1A1NPC1GAAMCOLN3LMNA | |
| SCHEMBL7578741 | 0.78 | BRAF (0.68) | ALDH1A1NPC1GAAMCOLN3LMNA | |
| SCHEMBL5410713 | 0.76 | MCOLN3 (0.78) | ALDH1A1GAAMCOLN3LMNAMEN1 | |
| SCHEMBL4709087 | 0.76 | MEN1 (0.84) | ALDH1A1GAALMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120064062-A1 | INHIBITORS OF BACTERIAL PLASMINOGEN ACTIVATORS | MICROBIOTIX, INC. | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120064062-A1 | INHIBITORS OF BACTERIAL PLASMINOGEN ACTIVATORS | PLG, PLAU, TFPI | ALDH1A1 4200/4885NPC1 3830/4885GAA 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.