Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 1/20 | 0.56 |
| ▸ | PLAU | P00749 | 1/20 | 0.56 |
| ▸ | PLAT | P00750 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 1/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29771149 | 1.00 | L3MBTL1 (0.63) | L3MBTL1KMT2AGAATHRBALDH1A1 | |
| SCHEMBL3028110 | 0.85 | KMT2A (0.67) | L3MBTL1KMT2AGAATHRBALDH1A1 | |
| SCHEMBL27129636 | 0.85 | L3MBTL1 (0.67) | L3MBTL1KMT2AGAATHRBALDH1A1 | |
| SCHEMBL6398309 | 0.85 | KMT2A (0.71) | KMT2AGAAALDH1A1SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL29079546 | 0.83 | KMT2A (0.69) | KMT2AGAAALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL30322798 | 0.83 | ALDH1A1 (0.69) | L3MBTL1KMT2AGAATHRBALDH1A1 | |
| Methane SCHEMBL28308571 | 0.83 | KMT2A (0.69) | KMT2AGAAALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL129889 | 0.83 | ALDH1A1 (0.69) | L3MBTL1KMT2AGAATHRBALDH1A1 | |
| SCHEMBL22890327 | 0.83 | KMT2A (0.64) | KMT2AGAATHRBALDH1A1SMN1; SMN2 | |
| SCHEMBL346217 | 0.83 | KMT2A (0.64) | KMT2AGAATHRBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773768-B1 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS INC (US) | 2018-08-22 | — | — | EP | claimed |
| CN-105875609-A | Agricultural fungicide | 重庆市赛欧生态农业有限公司 | 2016-08-24 | — | — | CN | claimed |
| CN-102179027-B | Ferrocene extinguishing composition | SHANNXI J & R FIRE PROT CO LTD | 2012-06-27 | — | — | CN | claimed |
| CN-102179027-A | Ferrocene extinguishing composition | SHANNXI J & R FIRE PROT CO LTD | 2011-09-14 | — | — | CN | claimed |
| EP-1773768-A4 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS INC (US) | 2008-08-06 | — | — | EP | claimed |
| CN-1312991-C | Agricultural bactericidal agent | INST OCEANOLOGY CHINESE ACAD (CN) | 2007-05-02 | — | — | CN | claimed |
| EP-1773768-A2 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | Exelixis, Inc. (US) | 2007-04-18 | — | — | EP | claimed |
| CN-1745629-A | A kind of agricultural bacteriocide | MARINE INST CHINESE ACADEMY OF (CN) | 2006-03-15 | — | — | CN | claimed |
| WO-2006012642-A2 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS, INC. (US) | 2006-02-02 | — | — | WO | claimed |
| EP-0622672-B1 | Photographic colour couplers, methods of making them and photographic materials containing them | KODAK LTD (GB) | 1998-02-11 | — | — | EP | claimed |
| US-5491049-A | COLOR COUPLER CONTAINS A DOUBLE BOND VINYL TO A SECONDARY AMINE GROUP | EASTMAN KODAK COMPANY (US) | 1996-02-13 | — | — | US | claimed |
| EP-0622672-A1 | Photographic colour couplers, methods of making them and photographic materials containing them | KODAK LIMITED (GB) | 1994-11-02 | — | — | EP | claimed |
| WO-2022160138-A1 | BENZOXAZINE-4-ONE COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 承德医学院 | 2022-08-04 | — | — | WO | disclosed |
| CN-112442022-B | Benzoxazine-4-ketone compound, preparation method and medical application thereof | 承德医学院 | 2022-05-20 | — | — | CN | disclosed |
| CN-112442022-A | Benzoxazine-4-ketone compound, preparation method and medical application thereof | 承德医学院 | 2021-03-05 | — | — | CN | disclosed |
| EP-1773768-B1 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS INC (US) | 2018-08-22 | — | — | EP | disclosed |
| WO-1990003379-A1 | PHOTOCHROMIC SUBSTANCES | OPTISCHE WERKE G. RODENSTOCK (DE) | 1990-04-05 | — | — | WO | disclosed |
| EP-0222274-B1 | 2-HYDROXYBENZAMIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-08-17 | — | — | EP | disclosed |
| EP-0260939-A2 | Molecules with antibody combining sites that exhibit catalytic properties | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1988-03-23 | — | — | EP | disclosed |
| EP-0222274-A1 | 2-Hydroxybenzamides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-05-20 | — | — | EP | disclosed |