SCHEMBL129889

SCHEMBL129889

O=C(O)c1cc([N+](=O)[O-])ccc1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.69
TDP1 Q9NUW8 3/20 0.69
SMN1; SMN2 Q16637 3/20 0.69
L3MBTL1 Q9Y468 1/20 0.65
CYP3A4 P08684 1/20 0.61
ALOX15 P16050 1/20 0.61
MAPT P10636 2/20 0.60
TP53 P04637 2/20 0.58
GPR35 Q9HC97 2/20 0.58
HPGD P15428 1/20 0.58
TSHR P16473 1/20 0.58
MAPK1 P28482 1/20 0.58
GAA P10253 2/20 0.56
THRB P10828 1/20 0.56
HTT P42858 1/20 0.55
CTSV O60911 1/20 0.55
CTSL P07711 1/20 0.55
KMT2A Q03164 2/20 0.54
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30322798 1.00 ALDH1A1 (0.69) ALDH1A1TDP1SMN1; SMN2L3MBTL1CYP3A4
SCHEMBL8410965 0.98 ALDH1A1 (0.67) ALDH1A1TDP1SMN1; SMN2L3MBTL1CYP3A4
SCHEMBL27673644 0.98 ALDH1A1 (0.67) ALDH1A1TDP1SMN1; SMN2L3MBTL1CYP3A4
SCHEMBL27653666 0.98 ALDH1A1 (0.67) ALDH1A1TDP1SMN1; SMN2L3MBTL1CYP3A4
SCHEMBL27673750 0.98 ALDH1A1 (0.67) ALDH1A1TDP1SMN1; SMN2L3MBTL1CYP3A4
SCHEMBL6393919 0.98 ALDH1A1 (0.67) ALDH1A1TDP1SMN1; SMN2L3MBTL1CYP3A4
Potassium Ion SCHEMBL8410957 0.96 ALDH1A1 (0.65) ALDH1A1TDP1SMN1; SMN2L3MBTL1CYP3A4
SCHEMBL27129636 0.86 L3MBTL1 (0.67) ALDH1A1TDP1SMN1; SMN2L3MBTL1CYP3A4
Aminobenzoic Acid SCHEMBL11348031 0.86 TDP1 (0.56) ALDH1A1TDP1SMN1; SMN2L3MBTL1CYP3A4
SCHEMBL4829731 0.86 TDP1 (0.66) ALDH1A1TDP1SMN1; SMN2L3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1722 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12533430-B2 Metal nuclide-loaded carbon microsphere (CMS), preparation method, and use thereof Chengdu New Radiomedicine Technology Co., Ltd. (CN) 2026-01-27 US claimed
US-12529648-B2 Colored reagent complex and method of detecting a rust removing agent in metal working fluids using the same NORTHERN TECHNOLOGIES INTERNATIONAL CORPORATION (US) 2026-01-20 US claimed
EP-4082580-B1 CARBON MICROBEAD LOADED WITH METAL NUCLIDE, PREPARATION METHOD, AND APPLICATION CHENGDU NEW RADIOMEDICINE TECH CO LTD (CN) 2025-09-10 EP claimed
US-20250214921-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND KAO CORPORATION (JP) 2025-07-03 US claimed
CN-119930435-A Preparation method of mesalamine intermediate 珠海润都制药股份有限公司 2025-05-06 CN claimed
CN-119613346-A Method for preparing 5-bromopyrimidine 上海沃缨生物科技有限公司 2025-03-14 CN claimed
EP-4501896-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND Kao Corporation (JP) 2025-02-05 EP claimed
EP-3946461-B1 XYLOGLUCAN-CONTAINING PRODRUGS AND METHODS OF MANUFACTURE AND USE THEREOF UNIV BRITISH COLUMBIA (CA) 2025-01-15 EP claimed
CN-119241604-A Organic-inorganic hybrid { Ti3In}xCrystalline state titanium indium oxide cluster patterning material and preparation method and application thereof 中国科学院福建物质结构研究所 2025-01-03 CN claimed
EP-4112085-B1 VISUALIZED RADIOACTIVE CARBON MICROSPHERE, AND PREPARATION METHOD AND APPLICATION THEREOF CHENGDU NEW RADIOMEDICINE TECH CO LTD (CN) 2024-12-11 EP claimed
CN-1132197-A 3,3'-azo-bi-(6-hydroxy benzoic acid) SHANGHAI CHINESE AND WESTERN M (CN) 1996-10-02 CN claimed
EP-0519971-A1 NOVEL PHARMACEUTICALLY ACTIVE COMPOUNDS WHICH CAN BE FORMED FROM 1,3,4,6,7,8-HEXAHYDRO-2H-PYRIMIDO-(1,2-a)-PYRIMIDINE. EEC PHARMA SA (FR) 1992-12-30 EP claimed
WO-1991013886-A1 NOVEL PHARMACEUTICALLY ACTIVE COMPOUNDS WHICH CAN BE FORMED FROM 1,3,4,6,7,8-HEXAHYDRO-2H-PYRIMIDO-(1,2-a)-PYRIMIDINE EEC-PHARMA S.A. (FR) 1991-09-19 WO claimed
US-4837229-A ANTIINFLAMMATORY AGENTS IN GASTROINTESTINAL TRACT HENNING BERLIN GMBH CHEMIE- UND PHARMAWERK (DE) 1989-06-06 US claimed
WO-1988009398-A1 ELECTROCHEMICAL SYNTHESIS OF SUBSTITUTED AMINES IN BASIC MEDIA THE DOW CHEMICAL COMPANY (US) 1988-12-01 WO claimed
EP-0291865-A2 Electrochemical synthesis of substituted aromatic amines in basic media THE DOW CHEMICAL COMPANY (US) 1988-11-23 EP claimed
US-4764263-A Electrochemical synthesis of substituted aromatic amines in basic media THE DOW CHEMICAL COMPANY (US) 1988-08-16 US claimed
US-4302521-A TRANSPORT PHASE OF A P-TYPE ORGANIC SEMICONDUCTOR, POLYVINYLCARBAZOLE, A LEWIS AND A BRONSTED ACID; CHARGE TRANSFER COMPOUNDS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-11-24 US claimed
US-4025609-A CHELATION KAO SOAP CO., LTD. (JA) 1977-05-24 US claimed
US-3997342-A Photoconductive element exhibiting persistent conductivity EASTMAN KODAK COMPANY (US) 1976-12-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533430-B2 Metal nuclide-loaded carbon microsphere (CMS), preparation method, and use thereof CPS1, SRM, NES ALDH1A1 1172/4885TDP1 3323/4885SMN1; SMN2 1730/4885
US-20250214921-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND HSD17B7, HSD17B12, BCKDK ALDH1A1 699/4885TDP1 4141/4885SMN1; SMN2 4516/4885
US-12529648-B2 Colored reagent complex and method of detecting a rust removing agent in metal working fluids using the same TST, RUVBL1, RUVBL2 ALDH1A1 1316/4885TDP1 4453/4885SMN1; SMN2 2972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.