Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4639633 | 0.85 | L3MBTL1 (0.63) | KMT2AGPR35GAATHRBALDH1A1 | |
| SCHEMBL29771149 | 0.85 | L3MBTL1 (0.63) | KMT2AGPR35GAATHRBALDH1A1 | |
| SCHEMBL6398309 | 0.85 | KMT2A (0.71) | KMT2AGAAALDH1A1CYP3A4ALOX15 | |
| SCHEMBL28263745 | 0.84 | GPR35 (0.55) | KMT2AGPR35GAATHRBALDH1A1 | |
| Hydrochloric Acid SCHEMBL29079546 | 0.83 | KMT2A (0.69) | KMT2AGAAALDH1A1CYP3A4ALOX15 | |
| SCHEMBL578933 | 0.83 | ALDH1A1 (0.66) | KMT2AGPR35GAATHRBALDH1A1 | |
| Methane SCHEMBL28308571 | 0.83 | KMT2A (0.69) | KMT2AGAAALDH1A1CYP3A4ALOX15 | |
| Hexanoate SCHEMBL27991725 | 0.82 | KMT2A (0.48) | KMT2AGAAALDH1A1CYP3A4ALOX15 | |
| SCHEMBL28709886 | 0.81 | ALDH1A1 (0.57) | KMT2AGPR35ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL1644789 | 0.81 | GPR35 (0.56) | KMT2AGPR35GAATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111138376-A | 3, 5-disubstituted phenyl-1, 2, 4-oxadiazole derivative and preparation method and application thereof | 中山大学 | 2020-05-12 | — | — | CN | disclosed |
| EP-2179994-B1 | FUSED BICYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2013-06-26 | — | — | EP | disclosed |
| CN-101809005-B | Fused bicyclic compound | MITSUBISHI TANABE PHARMA CORP | 2013-05-01 | — | — | CN | disclosed |
| US-8410166-B2 | Fused bicyclic compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-04-02 | — | — | US | disclosed |
| US-20130029979-A1 | FUSED BICYCLIC COMPOUND | TAKAHASHI YOICHI (JP) | 2013-01-31 | — | — | US | disclosed |
| US-8258131-B2 | Fused bicyclic compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-09-04 | — | — | US | disclosed |
| CN-101809005-A | Fused bicyclic compound | MITSUBISHI TANABE PHARMA CORP | 2010-08-18 | — | — | CN | disclosed |
| US-20100204218-A1 | FUSED BICYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-08-12 | — | — | US | disclosed |
| EP-2179994-A1 | FUSED BICYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130029979-A1 | FUSED BICYCLIC COMPOUND | NR3C2, NR3C1, MC2R | KMT2A 1022/4885GPR35 169/4885GAA 4864/4885 |
| US-20100204218-A1 | FUSED BICYCLIC COMPOUND | NR3C2, NR3C1, MC2R | KMT2A 1288/4885GPR35 176/4885GAA 4866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.