SCHEMBL4640169

SCHEMBL4640169

Cc1cscn1.c1ccc(-c2cscn2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.59
ALDH1A1 P00352 2/20 0.59
METAP2 P50579 2/20 0.44
METAP1 P53582 2/20 0.44
SCN9A Q15858 1/20 0.41
KDM4E B2RXH2 2/20 0.40
HSD17B10 Q99714 1/20 0.40
KAT6A Q92794 1/20 0.40
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
FKBP1A P62942 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HIF1A Q16665 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL679707 0.88 SCN9A (0.47) TSHRALDH1A1METAP2METAP1SCN9A
Methane SCHEMBL27495181 0.86 ALDH1A1 (0.47) TSHRALDH1A1METAP2METAP1SCN9A
SCHEMBL8944146 0.80 METAP2 (0.40) TSHRALDH1A1METAP2METAP1SCN9A
SCHEMBL27732241 0.78 KAT6A (0.49) TSHRALDH1A1METAP2METAP1SCN9A
SCHEMBL7492735 0.77 KAT6A (0.43) TSHRALDH1A1METAP2METAP1SCN9A
SCHEMBL27968 0.77
SCHEMBL10284703 0.76 KMT2A (0.48) TSHRALDH1A1METAP2METAP1SCN9A
Oxamate SCHEMBL9830672 0.75 KAT6A (0.47) ALDH1A1METAP1SCN9AKDM4EHSD17B10
SCHEMBL16159517 0.75 NPC1 (0.41) TSHRALDH1A1METAP2METAP1SCN9A
Bromide SCHEMBL4254817 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3977880-A Direct-positive emulsion containing silver halide grains internally doped with metal ions, surface ripened with gold and sulfur compound and fogged by light exposure FUJI PHOTO FILM CO., LTD. (JA) 1976-08-31 US claimed
EP-1298490-B1 Photopolymerizable composition and recording material FUJIFILM CORP (JP) 2008-08-13 EP disclosed
US-6756177-B2 MULTICOLOR RECORDING FUJI PHOTO FILM CO., LTD. (JP) 2004-06-29 US disclosed
US-20030129521-A1 Photopolymerizable composition and recording material FUJI PHOTO FILM CO., LTD. 2003-07-10 US disclosed
EP-1298490-A2 Photopolymerizable composition and recording material Fuji Photo Film Co., Ltd. (JP) 2003-04-02 EP disclosed