Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | METAP2 | P50579 | 2/20 | 0.46 |
| ▸ | METAP1 | P53582 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL27495181 | 0.98 | ALDH1A1 (0.47) | SCN9ARAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL27732241 | 0.88 | KAT6A (0.49) | SCN9ARAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL4640169 | 0.88 | TSHR (0.59) | SCN9ARAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL16159517 | 0.85 | NPC1 (0.41) | SCN9ARAB9ANPC1SMN1; SMN2KDM4E | |
| Oxamate SCHEMBL9830672 | 0.85 | KAT6A (0.47) | SCN9AKDM4EMETAP1KAT6AALDH1A1 | |
| SCHEMBL7492735 | 0.84 | KAT6A (0.43) | SCN9ARAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL16159141 | 0.84 | SCN9A (0.42) | SCN9ARAB9ANPC1SMN1; SMN2KDM4E | |
| Quinoline SCHEMBL27587533 | 0.82 | ALDH1A1 (0.55) | SCN9ARAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL8944146 | 0.82 | METAP2 (0.40) | SCN9ARAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL16159656 | 0.81 | METAP2 (0.40) | SCN9ARAB9ANPC1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260048071-A1 | 12-LIPOXYGENASE INHIBITORS FOR THE TREATMENT OF LUPUS | Cadrenal Therapeutics, Inc. | 2026-02-19 | — | — | US | claimed |
| US-20260027123-A1 | Compositions for Modulating Lipoxygenase and Methods of Using Same | UNIV CALIFORNIA (US) | 2026-01-29 | — | — | US | claimed |
| EP-4615432-A2 | 12-LIPOXYGENASE INHIBITORS FOR THE TREATMENT OF LUPUS | Veralox Therapeutics Inc. (US) | 2025-09-17 | — | — | EP | claimed |
| EP-4612135-A1 | ORAL PHARMACEUTICAL FORMULATIONS CONTAINING 4-((2-HYDROXY-3-METHOXYBENZYL)AMINO) BENZENESULFONAMIDE DERIVATIVES | Veralox Therapeutics Inc. (US) | 2025-09-10 | — | — | EP | claimed |
| EP-4558508-A1 | COMPOSITIONS FOR MODULATING LIPOXYGENASE AND METHODS OF USING SAME | The Regents of the University of California (US) | 2025-05-28 | — | — | EP | claimed |
| CN-120040505-A | Phosphorus phenol ligand, phosphorus phenol complex, preparation method and application thereof, and ethylene polymerization method | 南开大学 | 2025-05-27 | — | — | CN | claimed |
| CN-119192699-A | Latex composite resin composition for 3D printing and preparation method and application thereof | 中国科学院福建物质结构研究所 | 2024-12-27 | — | — | CN | claimed |
| CN-118976027-A | Application of aminothiazole derivative in preparation of medicine for treating neurodegenerative diseases | 武汉亿诺药业有限公司 | 2024-11-19 | — | — | CN | claimed |
| CN-118903136-A | Application of aminothiazole compound in preparation of medicine for treating xerophthalmia and medicine composition | 武汉亿诺药业有限公司 | 2024-11-08 | — | — | CN | claimed |
| WO-2024103023-A2 | 12-LIPOXYGENASE INHIBITORS FOR THE TREATMENT OF LUPUS | VERALOX THERAPEUTICS (US) | 2024-05-16 | — | — | WO | claimed |
| JP-2005533066-A | — | — | 2005-11-04 | — | — | JP | claimed |
| EP-1527070-A1 | AZOLE METHYLIDENE CYANIDE DERIVATIVES AND THEIR USE AS PROTEIN KINASE MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2005-05-04 | — | — | EP | claimed |
| WO-2003106455-A1 | AZOLE METHYLIDENE CYANIDE DERIVATIVES AND THEIR USE AS PROTEIN KINASE MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-12-24 | — | — | WO | claimed |
| US-5142545-A | LASER DYE | LAMBDA PHYSIK GESELLSCHAFT ZUR HERSTELLUNG VON LASERN MBH (DE) | 1992-08-25 | — | — | US | claimed |
| EP-0263020-B1 | 4-PHENYL THIAZOLE DERIVATIVES | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1990-07-25 | — | — | EP | claimed |
| US-4891305-A | LASERS | RICOH CO., LTD. (JP) | 1990-01-02 | — | — | US | claimed |
| US-4847274-A | CENTRAL NERVOUS SYSTEM, SEDATIVES | LABORATOIRE L. LAFON (FR) | 1989-07-11 | — | — | US | claimed |
| EP-0263020-A1 | 4-Phenyl thiazole derivatives | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1988-04-06 | — | — | EP | claimed |
| US-4102688-A | CONTAINING PYRAZOLO(3,4-B)PYRIDINE/3,6-DIONE MOIETY | FUJI PHOTO FILM CO., LTD. (JP) | 1978-07-25 | — | — | US | claimed |
| US-3970461-A | Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus | FUJI PHOTO FILM CO., LTD. (JA) | 1976-07-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260048071-A1 | 12-LIPOXYGENASE INHIBITORS FOR THE TREATMENT OF LUPUS | ALOX12, ALOX5, ALOX15 | SCN9A 4039/4885RAB9A 4472/4885NPC1 2086/4885 |
| US-20260027123-A1 | Compositions for Modulating Lipoxygenase and Methods of Using Same | ALOX12, ALOX15, ALOX15B | SCN9A 3669/4885RAB9A 4241/4885NPC1 1396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.