Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27539135 | 0.84 | LMNA (0.40) | NPC1RAB9AL3MBTL1PDE4BSMN1; SMN2 | |
| SCHEMBL27516569 | 0.83 | LMNA (0.53) | NPC1RAB9AL3MBTL1TSHRADORA2A | |
| SCHEMBL17360640 | 0.80 | HDAC1 (0.54) | NPC1RAB9ANOTUMKMT2ASMN1; SMN2 | |
| SCHEMBL28742829 | 0.78 | HPGD (0.41) | FFAR1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL4640428 | 0.76 | MAPK1 (0.47) | NPC1RAB9AL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL1544536 | 0.76 | HDAC1 (0.50) | FFAR1IKBKBNOTUMPDE4BTP53 | |
| SCHEMBL2868465 | 0.74 | ADRB2 (0.55) | FFAR1IKBKBNPC1RAB9AL3MBTL1 | |
| SCHEMBL27515881 | 0.74 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL27539429 | 0.74 | MAPT (0.35) | NPC1RAB9AL3MBTL1PTGS2KMT2A | |
| SCHEMBL28815027 | 0.74 | HDAC1 (0.37) | NPC1RAB9APDE4BSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101723941-A | “1,2,4” oxadiazole as a metabotropic glutamate receptor-5 modulator | ASTRAZENECA AB | 2010-06-09 | — | — | CN | disclosed |