Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4642372 | 0.86 | GPR84 (0.50) | GPR84TACR1TNFALDH1A1LMNA | |
| SCHEMBL4640366 | 0.81 | ALDH1A1 (0.46) | GPR84ALDH1A1LMNAMTNR1AMTNR1B | |
| SCHEMBL4240366 | 0.76 | GPR84 (0.37) | GPR84TACR1ALDH1A1RECQL | |
| SCHEMBL4234106 | 0.76 | GPR84 (0.39) | GPR84TACR1ALDH1A1RECQL | |
| SCHEMBL837254 | 0.75 | MPO (0.40) | GPR84TACR1ALDH1A1LMNA | |
| SCHEMBL5365453 | 0.74 | ALDH1A1 (0.42) | TACR1ALDH1A1RECQL | |
| SCHEMBL5359741 | 0.72 | ALDH1A1 (0.43) | ALDH1A1LMNARECQL | |
| SCHEMBL5361416 | 0.72 | ALDH1A1 (0.43) | ALDH1A1RECQL | |
| SCHEMBL4236247 | 0.72 | ALDH1A1 (0.34) | ALDH1A1MTNR1AMTNR1BRECQL | |
| SCHEMBL2036829 | 0.71 | LRRK2 (0.34) | ALDH1A1MTNR1ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207728-A1 | BICYCLIC ACYLTRYPTOPHANOLS | BAYER SCHERING PHARMA AG (DE) | 2008-08-28 | — | — | US | disclosed |
| EP-1956016-A1 | Bicyclic acyltryptophanols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207728-A1 | BICYCLIC ACYLTRYPTOPHANOLS | FSHR, GNRHR, TPH1 | GPR84 304/4885TACR1 101/4885TNF 1517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.