Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18281275 | 0.97 | TSHR (0.48) | TSHRCHRM2ALDH1A1TDP1LCK | |
| SCHEMBL9797780 | 0.92 | TSHR (0.43) | TSHRCHRM2ALDH1A1TDP1LCK | |
| SCHEMBL14040492 | 0.92 | CHRM2 (0.46) | TSHRCHRM2ALDH1A1TDP1LCK | |
| SCHEMBL3456909 | 0.92 | CHRM2 (0.46) | TSHRCHRM2ALDH1A1TDP1LCK | |
| SCHEMBL16892353 | 0.89 | CHRM2 (0.42) | TSHRCHRM2ALDH1A1TDP1LCK | |
| SCHEMBL2824702 | 0.84 | TSHR (0.37) | TSHRCHRM2ALDH1A1HPGDMAPT | |
| SCHEMBL21077931 | 0.84 | TSHR (0.48) | TSHRCHRM2SIGMAR1S1PR2S1PR1 | |
| SCHEMBL2827056 | 0.82 | CHRM2 (0.38) | TSHRCHRM2ALDH1A1HPGDMAPT | |
| SCHEMBL5613764 | 0.80 | TSHR (0.50) | TSHRCHRM2ALDH1A1LCKHPGD | |
| SCHEMBL150143 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1419136-B1 | POLYAMINES AND POLYMERS MADE THEREWITH | INVISTA TECH SARL (CH) | 2008-08-06 | — | — | EP | disclosed |
| US-6812325-B2 | POLYAMIDES BASED ON DIAMINES HAVING TERTIARY AMINES WITH ALIPHATIC OR AROMATIC SUBSTITUENTS AND A SEPARATION OF >4 CARBON ATOMS BETWEEN ANY TWO NITROGEN GROUPS; POLYESTER/NYLON ADDITIVE TO INCREASE DYEABILITY BY ACID/BASIC DYES | INVISTA NORTH AMERICA S.AR.L. | 2004-11-02 | — | — | US | disclosed |
| EP-1419136-A2 | POLYAMINES AND POLYMERS MADE THEREWITH | INVISTA Technologies S.à.r.l. (US) | 2004-05-19 | — | — | EP | disclosed |
| EP-1419196-A1 | ACID DYEABLE POLYMER COMPOSITIONS | INVISTA Technologies S.à.r.l. (US) | 2004-05-19 | — | — | EP | disclosed |
| US-6723799-B2 | BLENDS OF POLYESTER WITH NYLON; FIBERS, FABRICS AND FILMS | E I. DU PONT DE NEMOURS AND COMPANY | 2004-04-20 | — | — | US | disclosed |
| US-6713653-B2 | USEFUL FOR IMPROVING ACID-DYEABILITY OF POLYMER COMPOSITIONS, FIBERS, FABRICS, FILMS AND OTHER ARTICLES | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-03-30 | — | — | US | disclosed |
| US-20030208031-A1 | Polyamines and polymers made therewith | E.I. DU PONT DE NEMOURS AND COMPANY | 2003-11-06 | — | — | US | disclosed |
| US-20030083441-A1 | Acid dyeable polymer compositions | INVISTA NORTH AMERICA S.A.R.L. | 2003-05-01 | — | — | US | disclosed |
| WO-2003018689-A1 | ACID DYEABLE POLYMER COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-03-06 | — | — | WO | disclosed |
| US-20030045674-A1 | Polyamines and polymers made therewith | INVISTA NORTH AMERICA S.A.R.L. | 2003-03-06 | — | — | US | disclosed |
| WO-2003018533-A2 | POLYAMINES AND POLYMERS MADE THEREWITH | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030045674-A1 | Polyamines and polymers made therewith | PNISR, SRM, SMS | TSHR 2252/4885CHRM2 1413/4885ALDH1A1 1810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.