Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 4/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 2/20 | 0.31 |
| ▸ | RARG | P13631 | 2/20 | 0.31 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.31 |
| ▸ | RARA | P10276 | 2/20 | 0.31 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL136801 | 0.96 | MAPT (0.39) | MAPTTHRBRECQLMEN1LMNA | |
| SCHEMBL3867446 | 0.89 | TDP1 (0.39) | MAPTTHRBRECQLMEN1LMNA | |
| SCHEMBL3868600 | 0.86 | TDP1 (0.40) | MAPTTHRBRECQLMEN1LMNA | |
| SCHEMBL22664031 | 0.85 | MEN1 (0.45) | MAPTTHRBRECQLMEN1LMNA | |
| SCHEMBL12160878 | 0.84 | MEN1 (0.46) | MAPTTHRBRECQLMEN1LMNA | |
| SCHEMBL1714509 | 0.83 | MAPT (0.40) | MAPTTHRBRECQLMEN1LMNA | |
| SCHEMBL19063420 | 0.83 | MEN1 (0.40) | MAPTTHRBRECQLMEN1LMNA | |
| Iodide SCHEMBL1051835 | 0.83 | MEN1 (0.46) | MAPTTHRBRECQLMEN1LMNA | |
| Iodide SCHEMBL2587637 | 0.83 | MEN1 (0.48) | MAPTTHRBRECQLMEN1LMNA | |
| SCHEMBL3877735 | 0.83 | TDP1 (0.42) | MAPTTHRBRECQLMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1211294-B1 | Improved process and method for the preparation of asymmetric monofunctionalised indocyanine labelling reagents and obtained compounds | VISEN MEDICAL INC (US) | 2008-08-13 | — | — | EP | disclosed |
| US-20050245734-A1 | Process and method for the preparation of asymetric monfunctionalised indocyanine labelling reagents and obtained compounds | VISEN MEDICAL, INC. | 2005-11-03 | — | — | US | disclosed |
| US-6740755-B2 | REACTING FIRST QUATERNISED INDOLENINE WITH AN IMINE COMPOUND IN A SOLVENT SELECTED FROM ACETIC ACID, ACETIC ANHYDRIDE AND MIXTURES THEREOF, FURTHER REACTING INTERMEDIATE HEMICYANINE WITH QUATERNIZED INDOLINE | VISEN MEDICAL, INC. | 2004-05-25 | — | — | US | disclosed |
| EP-1211294-A1 | Improved process and method for the preparation of asymmetric monofunctionalised indocyanine labelling reagents and obtained compounds | Innosense S.r.l. (IT) | 2002-06-05 | — | — | EP | disclosed |
| EP-1209205-A1 | Improved process and method for the preparation of asymetric monofunctionalised indocyanine labelling reagents and obtained compounds | Innosense S.r.l. (IT) | 2002-05-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245734-A1 | Process and method for the preparation of asymetric monfunctionalised indocyanine labelling reagents and obtained compounds | IDO1, IDO2, AADAT | MAPT 4620/4885THRB 3290/4885RECQL 1586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.