Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 4/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12160878 | 0.99 | MEN1 (0.46) | MEN1LMNAMAPTTHRBHTT | |
| Iodide SCHEMBL1051835 | 0.95 | MEN1 (0.46) | MEN1LMNAMAPTTHRBHTT | |
| Iodide SCHEMBL19817517 | 0.95 | MEN1 (0.46) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL22664031 | 0.95 | MEN1 (0.45) | MEN1LMNAMAPTTHRBHTT | |
| Iodide SCHEMBL20975474 | 0.87 | THRB (0.47) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL29271029 | 0.85 | THRB (0.44) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL3868600 | 0.85 | TDP1 (0.40) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL19063420 | 0.85 | MEN1 (0.40) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL3867446 | 0.84 | TDP1 (0.39) | MEN1LMNAMAPTTHRBHTT | |
| SCHEMBL136801 | 0.84 | MAPT (0.39) | MEN1LMNAMAPTTHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404842-B2 | Organic and inorganic photosensitizer dyes | NATIONAL CENTRAL UNIVERSITY (TW) | 2013-03-26 | — | — | US | disclosed |
| CN-102286212-A | Organic and inorganic photosensitive dyes | — | 2011-12-21 | — | — | CN | disclosed |
| US-20110288300-A1 | Organic and inorganic photosensitizer dyes | NAIONAL CENTRAL UNIVERSITY (TW) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288300-A1 | Organic and inorganic photosensitizer dyes | IK, TYR, CRY1 | MEN1 2830/4885LMNA 3574/4885MAPT 803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.