SCHEMBL4640771

SCHEMBL4640771

CCCC(CC)OC(=O)c1cccc(CC)c1C(=O)OC(CC)CCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 2/20 0.46
PRKCD Q05655 2/20 0.46
KMT2A Q03164 1/20 0.39
UTS2R Q9UKP6 1/20 0.38
ALDH1A1 P00352 3/20 0.37
CA2 P00918 2/20 0.37
CYP3A4 P08684 1/20 0.37
ADRA1A P35348 1/20 0.36
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35
PRSS3 P35030 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
TAS1R3 Q7RTX0 2/20 0.35
TAS1R1 Q7RTX1 2/20 0.35
LMNA P02545 1/20 0.34
TSHR P16473 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4640755 0.92 PRKCA (0.44) PRKCAPRKCDKMT2AUTS2RALDH1A1
SCHEMBL4640002 0.89 KMT2A (0.38) PRKCAPRKCDKMT2AUTS2RALDH1A1
SCHEMBL4641098 0.86 PRKCA (0.46) PRKCAPRKCDKMT2AUTS2RALDH1A1
SCHEMBL4640690 0.84 PRKCA (0.45) PRKCAPRKCDKMT2AALDH1A1CA2
SCHEMBL4640625 0.84 PRKCA (0.45) PRKCAPRKCDKMT2AUTS2RALDH1A1
SCHEMBL4640772 0.84 PRKCA (0.45) PRKCAPRKCDKMT2AALDH1A1CA2
SCHEMBL234033 0.83 PRKCA (0.54) PRKCAPRKCDKMT2AALDH1A1CA2
SCHEMBL4641312 0.82 PRKCA (0.43) PRKCAPRKCDKMT2AALDH1A1CA2
SCHEMBL4640003 0.81 ALDH1A1 (0.40) PRKCAPRKCDKMT2AUTS2RALDH1A1
SCHEMBL4641100 0.81 PRKCA (0.44) PRKCAPRKCDKMT2AUTS2RALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1188739-B1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO LTD (JP) 2008-08-13 EP disclosed
US-6670497-B2 Dialkyl (at least one of which is a C4-8 tertiary alkyl) ester of an alkyl- or halo-substituted phthalic acid; used in an olefin polymerization catalyst TOHO TITANIUM CO., LTD. (JP) 2003-12-30 US disclosed
US-20030036594-A1 Phthalic diester derivatives and electron donors TOHO TITANIUM CO., LTD. (JP) 2003-02-20 US disclosed
EP-1188739-A1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO., LTD. (JP) 2002-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030036594-A1 Phthalic diester derivatives and electron donors HPD, ETFA, PPOX PRKCA 1200/4885PRKCD 552/4885KMT2A 3313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.