Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640829 | 0.93 | MEN1 (0.37) | METAP2MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL4640014 | 0.87 | ALDH1A1 (0.44) | METAP2MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL4641293 | 0.86 | CSNK2A1 (0.41) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4640103 | 0.86 | METAP2 (0.40) | METAP2MEN1KMT2AALDH1A1USP2 | |
| SCHEMBL4639939 | 0.85 | KDM4E (0.40) | ALDH1A1HPGDSMN1; SMN2AKR1C2 | |
| SCHEMBL4639930 | 0.85 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL4642995 | 0.84 | MEN1 (0.35) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL4640001 | 0.82 | SMN1; SMN2 (0.36) | MEN1KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL15675541 | 0.82 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL4640470 | 0.82 | AKR1C3 (0.41) | METAP2MEN1KMT2AALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188739-B1 | PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS | TOHO TITANIUM CO LTD (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-6670497-B2 | Dialkyl (at least one of which is a C4-8 tertiary alkyl) ester of an alkyl- or halo-substituted phthalic acid; used in an olefin polymerization catalyst | TOHO TITANIUM CO., LTD. (JP) | 2003-12-30 | — | — | US | disclosed |
| US-20030036594-A1 | Phthalic diester derivatives and electron donors | TOHO TITANIUM CO., LTD. (JP) | 2003-02-20 | — | — | US | disclosed |
| EP-1188739-A1 | PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS | TOHO TITANIUM CO., LTD. (JP) | 2002-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030036594-A1 | Phthalic diester derivatives and electron donors | HPD, ETFA, PPOX | METAP2 4546/4885MEN1 3562/4885KMT2A 3313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.