Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.90 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.90 |
| ▸ | FOS | P01100 | 2/20 | 0.73 |
| ▸ | TTR | P02766 | 2/20 | 0.73 |
| ▸ | JUN | P05412 | 2/20 | 0.73 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.73 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.73 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylnordihydroguarierate Acid SCHEMBL22039401 | 0.95 | ALOX15 (1.00) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL22040032 | 0.92 | ALOX15 (1.00) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL2390 | 0.90 | FOS (0.90) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL16917560 | 0.90 | FOS (0.90) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL3160 | 0.90 | ALOX15 (0.90) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL31237435 | 0.90 | FOS (0.90) | ALOX15ALOX12FOSTTRJUN | |
| Terameprocol SCHEMBL2356280 | 0.89 | ALOX15 (0.77) | ALOX15ALOX12FOSTTRJUN | |
| Terameprocol SCHEMBL29794162 | 0.89 | ALOX15 (0.77) | ALOX15ALOX12FOSTTRJUN | |
| Terameprocol SCHEMBL194588 | 0.89 | ALOX15 (0.77) | ALOX15ALOX12FOSTTRJUN | |
| Terameprocol SCHEMBL10060164 | 0.89 | ALOX15 (0.77) | ALOX15ALOX12FOSTTRJUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE40246-E1 | Method for the suppression of viral growth | JOHN HOPKINS UNIVERSITY (US) | 2008-04-15 | — | — | US | claimed |
| EP-0783474-B1 | COMPOUNDS FOR THE SUPPRESSION OF HIV TAT TRANSACTIVATION | UNIV JOHNS HOPKINS (US) | 2008-08-06 | — | — | EP | disclosed |
| US-RE40246-E1 | Method for the suppression of viral growth | JOHN HOPKINS UNIVERSITY (US) | 2008-04-15 | — | — | US | disclosed |
| US-RE40246-E1 | Method for the suppression of viral growth | JOHN HOPKINS UNIVERSITY (US) | 2008-04-15 | — | — | US | disclosed |
| US-6365787-B1 | CREOSOTE BUSH LARREA TRIDENTATA EXTRACTS OF 1,4-BIS-(3,4-DIHYDROXY-PHENYL)-2,3-DIMETHYLBUTANE DERIVATIVES | THE JOHNS HOPKINS UNIVERSITY | 2002-04-02 | — | — | US | disclosed |
| US-6291524-B1 | HYDROXY-, METHOXY- AND ACETOXY-DERIVATIVES OF 2,3-DIMETHYL-1,4-DIPHENYLBUTANE | JOHNS HOPKINS UNIVERSITY | 2001-09-18 | — | — | US | disclosed |
| US-5663209-A | Compounds for the suppression of HIV Tat transactivation | THE JOHNS HOPKINS UNIVERSITY (US) | 1997-09-02 | — | — | US | disclosed |
| WO-1996010549-A9 | COMPOUNDS FOR THE SUPPRESSION OF HIV TAT TRANSACTIVATION | — | 1996-06-06 | — | — | WO | disclosed |