Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640941 | 0.94 | ESR1 (0.32) | ESR1ESR2ARGAA | |
| SCHEMBL4641233 | 0.94 | ESR1 (0.32) | ESR1ESR2ARGAA | |
| SCHEMBL4640046 | 0.90 | ESR1 (0.35) | ESR1ESR2ARGAAMAPK1 | |
| SCHEMBL4640049 | 0.84 | GABRP (0.34) | ESR1ESR2 | |
| SCHEMBL4644128 | 0.84 | HSD17B10 (0.33) | GAA | |
| SCHEMBL4640807 | 0.83 | CA1 (0.35) | ESR1 | |
| SCHEMBL4641161 | 0.83 | TSHR (0.32) | ESR1 | |
| SCHEMBL4640842 | 0.83 | GRIN2D (0.33) | ESR1ESR2MAPK1 | |
| SCHEMBL4639955 | 0.83 | MTNR1A (0.33) | ESR1ESR2 | |
| SCHEMBL4640037 | 0.79 | NPC1 (0.35) | ESR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188739-B1 | PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS | TOHO TITANIUM CO LTD (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-6670497-B2 | Dialkyl (at least one of which is a C4-8 tertiary alkyl) ester of an alkyl- or halo-substituted phthalic acid; used in an olefin polymerization catalyst | TOHO TITANIUM CO., LTD. (JP) | 2003-12-30 | — | — | US | disclosed |
| US-20030036594-A1 | Phthalic diester derivatives and electron donors | TOHO TITANIUM CO., LTD. (JP) | 2003-02-20 | — | — | US | disclosed |
| EP-1188739-A1 | PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS | TOHO TITANIUM CO., LTD. (JP) | 2002-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030036594-A1 | Phthalic diester derivatives and electron donors | HPD, ETFA, PPOX | ESR1 168/4885ESR2 224/4885AR 2694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.