Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4915938 | 0.84 | ALDH1A1 (0.47) | MEN1KMT2ARAB9AEPHX2PPARG | |
| SCHEMBL4640487 | 0.83 | KMT2A (0.41) | MEN1KMT2ARAB9ACALCRLEPHX2 | |
| SCHEMBL4640794 | 0.73 | MEN1 (0.38) | MEN1KMT2ARAB9ACALCRLEPHX2 | |
| SCHEMBL4639963 | 0.70 | ADRB3 (0.42) | — | |
| SCHEMBL4398728 | 0.69 | MEN1 (0.45) | MEN1KMT2AEPHX2PPARGHTR1A | |
| SCHEMBL891295 | 0.68 | DYRK1A (0.49) | CALCRLL3MBTL1 | |
| SCHEMBL13306513 | 0.68 | PDPK1 (0.56) | — | |
| SCHEMBL3390372 | 0.67 | MEN1 (0.51) | MEN1KMT2ARAB9ASMN1; SMN2HPGD | |
| SCHEMBL13306474 | 0.67 | CA12 (0.51) | MAOB | |
| SCHEMBL15183122 | 0.67 | CNR2 (0.48) | MEN1KMT2ARAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943229-A1 | BENZIMIDAZOLE DERIVATIVES FOR USE AS BETA-3 RECEPTOR AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007048842-A1 | BENZIMIDAZOLE DERIVATIVES FOR USE AS BETA-3 RECEPTOR AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-03 | — | — | WO | disclosed |