SCHEMBL4641561

SCHEMBL4641561

CC[CH]C(=O)Oc1c(Cl)cc(Cl)cc1I

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.32
MEN1 O00255 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
KDM4E B2RXH2 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2D6 P10635 2/20 0.32
NR1I2 O75469 1/20 0.32
ABCB1 P08183 1/20 0.32
ACLY P53396 1/20 0.31
MAPT P10636 3/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
ALDH1A1 P00352 2/20 0.31
POLB P06746 1/20 0.31
NLRP3 Q96P20 1/20 0.31
MRGPRX4 Q96LA9 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4643896 0.89 KMT2A (0.36) KMT2AMEN1TDP1KDM4ENR1I2
SCHEMBL4645706 0.88 AHR (0.31) KMT2AMEN1TDP1KDM4ECYP1A2
SCHEMBL4642631 0.83 KMT2A (0.34) KMT2AMEN1TDP1KDM4ECYP1A2
SCHEMBL28068647 0.80 ACLY (0.42) KMT2AMEN1TDP1KDM4ECYP1A2
SCHEMBL4644625 0.77 POLB (0.47) KMT2AMEN1TDP1MAPTCA1
SCHEMBL4643660 0.76 KMT2A (0.34) KMT2AMEN1TDP1KDM4ENR1I2
SCHEMBL4642406 0.76 POLB (0.38) KMT2AMEN1TDP1KDM4ECYP1A2
SCHEMBL4644524 0.74 ALDH1A1 (0.36) KMT2AMEN1TDP1KDM4ECYP1A2
SCHEMBL4641943 0.74 KMT2A (0.35) KMT2AMEN1TDP1KDM4ECYP1A2
SCHEMBL4644619 0.74 CA1 (0.36) KMT2AMEN1KDM4ECYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed