SCHEMBL4645706

SCHEMBL4645706

CCC[CH]C(=O)Oc1c(Cl)cc(Cl)cc1I

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.31
GALK1 P51570 1/20 0.31
KMT2A Q03164 5/20 0.31
MEN1 O00255 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
NR1I2 O75469 1/20 0.31
KDM4E B2RXH2 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
ABCB1 P08183 1/20 0.31
ACLY P53396 1/20 0.30
MAPT P10636 1/20 0.30
POLB P06746 1/20 0.30
THRB P10828 1/20 0.30
RECQL P46063 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4643660 0.90 KMT2A (0.34) AHRGALK1KMT2AMEN1TDP1
SCHEMBL4641561 0.88 KMT2A (0.32) KMT2AMEN1TDP1NR1I2KDM4E
SCHEMBL4642631 0.80 KMT2A (0.34) KMT2AMEN1TDP1KDM4ECYP1A2
SCHEMBL4644487 0.78 POLB (0.36) GALK1KMT2AMEN1KDM4ECYP1A2
SCHEMBL28068647 0.77 ACLY (0.42) KMT2AMEN1TDP1KDM4ECYP1A2
SCHEMBL4643896 0.77 KMT2A (0.36) KMT2AMEN1TDP1NR1I2KDM4E
SCHEMBL4644625 0.75 POLB (0.47) KMT2AMEN1TDP1MAPTPOLB
SCHEMBL4644078 0.74 HSD17B10 (0.36) KMT2AMEN1TDP1KDM4ECYP1A2
SCHEMBL4644524 0.72 ALDH1A1 (0.36) KMT2AMEN1TDP1KDM4ECYP1A2
SCHEMBL4641943 0.72 KMT2A (0.35) KMT2AMEN1TDP1KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed