Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.55 |
| ▸ | ITGAV | P06756 | 18/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640844 | 0.91 | ITGB3 (0.48) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6811091 | 0.90 | ITGB3 (0.53) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL4641094 | 0.89 | ITGB3 (0.55) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6802237 | 0.85 | ITGB3 (0.59) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6802240 | 0.85 | ITGB3 (0.59) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL4641449 | 0.85 | ITGB3 (0.59) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6804912 | 0.83 | ITGB3 (0.45) | ITGB3ITGAV | |
| SCHEMBL4640251 | 0.82 | ITGB3 (0.49) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL27524220 | 0.81 | ITGB3 (0.46) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL4640164 | 0.81 | ITGB3 (0.46) | ITGB3ITGAVITGA2BITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853084-B1 | Substituted purine derivatives as vitronectin receptor antagonists | HOECHST AG (DE) | 2008-08-13 | — | — | EP | disclosed |
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |
| EP-0853084-A2 | Substituted purine derivatives as vitronectin receptor antagonists | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-15 | — | — | EP | disclosed |