Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.45 |
| ▸ | ITGAV | P06756 | 11/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810547 | 0.90 | ITGB3 (0.40) | ITGB3ITGAVCNR1CNR2CCNE2 | |
| SCHEMBL6811105 | 0.90 | CNR1 (0.44) | ITGB3ITGAVCNR1CNR2CASP1 | |
| SCHEMBL6811574 | 0.89 | ITGB3 (0.45) | ITGB3ITGAVCNR1CNR2JAK2 | |
| SCHEMBL6802245 | 0.85 | ITGB3 (0.49) | ITGB3ITGAV | |
| SCHEMBL4641583 | 0.83 | ITGB3 (0.55) | ITGB3ITGAV | |
| SCHEMBL4640260 | 0.82 | ITGB3 (0.43) | ITGB3ITGAVCNR1CNR2 | |
| SCHEMBL6805979 | 0.80 | CNR1 (0.41) | ITGB3ITGAVCNR1CNR2PREP | |
| SCHEMBL4640844 | 0.79 | ITGB3 (0.48) | ITGB3ITGAV | |
| SCHEMBL6806539 | 0.79 | BTK (0.43) | CCNE2CCNA2CCNE1CDK2CCNA1 | |
| SCHEMBL6911764 | 0.76 | ADORA1 (0.40) | ITGB3ITGAVCNR1CNR2CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |