SCHEMBL4641982

SCHEMBL4641982

CCC[Si](CCC)(CCC)OC(=O)CCCO

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
CAMK2A Q9UQM7 1/20 0.34
LMNA P02545 3/20 0.33
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
MGLL Q99685 1/20 0.33
ACHE P22303 6/20 0.33
KDM4E B2RXH2 1/20 0.33
DUSP3 P51452 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644430 0.94 SMN1; SMN2 (0.38) DGKAMAPTMAPK1LMNAACHE
SCHEMBL4644612 0.90 DGKA (0.38) DGKAMAPTMAPK1LMNAALDH1A1
SCHEMBL4643700 0.89 DGKA (0.41) DGKAMAPTMAPK1LMNAALDH1A1
SCHEMBL4645703 0.88 ALDH1A1 (0.36) ALDH1A1
SCHEMBL4647907 0.87 DGKA (0.44) DGKAMAPTMAPK1LMNAALDH1A1
SCHEMBL4642000 0.87 DGKA (0.44) DGKAMAPTMAPK1LMNAALDH1A1
SCHEMBL4643596 0.85 DGKA (0.41) DGKAMAPTMAPK1LMNAALDH1A1
SCHEMBL4642132 0.83 CAMK2A (0.37) DGKAMAPTMAPK1CAMK2ALMNA
SCHEMBL4643819 0.83 DGKA (0.44) DGKAMAPTMAPK1LMNAALDH1A1
SCHEMBL4642480 0.82 DGKA (0.34) DGKAMAPTMAPK1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed