Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | RAB9A | P51151 | 5/20 | 0.68 |
| ▸ | HPGD | P15428 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.68 |
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | CASP3 | P42574 | 1/20 | 0.68 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.68 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.68 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31606761 | 1.00 | NPC1 (0.68) | NPC1ALDH1A1RAB9AHPGDKDM4E | |
| SCHEMBL31462147 | 1.00 | NPC1 (0.68) | NPC1ALDH1A1RAB9AHPGDKDM4E | |
| SCHEMBL1963361 | 0.89 | NPC1 (0.76) | NPC1ALDH1A1RAB9AHPGDKDM4E | |
| SCHEMBL11314930 | 0.89 | NPC1 (0.62) | NPC1ALDH1A1RAB9AHPGDKDM4E | |
| SCHEMBL11743614 | 0.87 | NPC1 (0.72) | NPC1ALDH1A1RAB9AHPGDKDM4E | |
| SCHEMBL22671318 | 0.86 | HDAC3 (0.61) | NPC1ALDH1A1RAB9AHPGDKDM4E | |
| SCHEMBL3690385 | 0.85 | HPGD (0.77) | NPC1ALDH1A1RAB9AHPGDKDM4E | |
| SCHEMBL392793 | 0.85 | NPC1 (0.70) | NPC1ALDH1A1RAB9AKDM4EHSD17B10 | |
| SCHEMBL4956879 | 0.84 | NPC1 (0.69) | NPC1ALDH1A1RAB9AHPGDKDM4E | |
| SCHEMBL17774960 | 0.84 | ALDH1A1 (0.63) | NPC1ALDH1A1RAB9AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661459-A | 1,2, 3-Benzotriazine-4 (3H) -one seleno compound and preparation method and application thereof | 赣南师范大学 | 2025-03-21 | — | — | CN | claimed |
| CN-104744379-B | A kind of quianzolinones and its synthetic method | 三峡大学 | 2017-10-27 | — | — | CN | claimed |
| CN-104829543-B | A kind of 2 (4 oxoalkyl group) quianzolinones and its synthetic method | 三峡大学 | 2017-08-25 | — | — | CN | claimed |
| CN-119661459-A | 1,2, 3-Benzotriazine-4 (3H) -one seleno compound and preparation method and application thereof | 赣南师范大学 | 2025-03-21 | — | — | CN | disclosed |
| CN-117510415-A | Synthesis method of quinazolinone compound | 中国人民解放军军事科学院防化研究院 | 2024-02-06 | — | — | CN | disclosed |
| CN-108822046-B | Method for synthesizing quinazolinone compound by one-pot method | 河南大学 | 2021-07-06 | — | — | CN | disclosed |
| WO-2020239050-A1 | 2-(2-CHLORO-4-METHYLPHENYL)QUINAZOLINE-4(3H)-KETONE COMPOUND AND MEDICAL USE THEREOF | 中国人民解放军军事科学院军事医学研究院 | 2020-12-03 | — | — | WO | disclosed |
| CN-110041273-B | 2- (2-chloro-4-methylphenyl) quinazoline-4 (3H) -ketone compound and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-10-20 | — | — | CN | disclosed |
| CN-110041273-A | 2- (the chloro- 4- aminomethyl phenyl of 2-) quinazoline -4 (3H) -one class compound and its medical usage | 中国人民解放军军事科学院军事医学研究院 | 2019-07-23 | — | — | CN | disclosed |
| CN-108822046-A | The method of one pot process quianzolinones | 河南大学 | 2018-11-16 | — | — | CN | disclosed |
| CN-104744379-B | A kind of quianzolinones and its synthetic method | 三峡大学 | 2017-10-27 | — | — | CN | disclosed |
| EP-1581467-A4 | LIGANDS FOR METALS AND IMPROVED METAL-CATALYZED PROCESSES BASED THEREON | MASSACHUSETTS INST TECHNOLOGY (US) | 2008-08-13 | — | — | EP | disclosed |
| US-7223879-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223879-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223879-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-05-29 | — | — | US | disclosed |
| CN-1745049-A | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INST TECHNOLOGY (US) | 2006-03-08 | — | — | CN | disclosed |
| EP-1581467-A2 | LIGANDS FOR METALS AND IMPROVED METAL-CATALYZED PROCESSES BASED THEREON | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-10-05 | — | — | EP | disclosed |
| US-20040171833-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | NATIONAL SCIENCE FOUNDATION | 2004-09-02 | — | — | US | disclosed |
| WO-2004052939-A2 | LIGANDS FOR METALS AND IMPROVED METAL-CATALYZED PROCESSES BASED THEREON | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2004-06-24 | — | — | WO | disclosed |
| US-4004029-A | BENZAMIDES | THE UPJOHN COMPANY (US) | 1977-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171833-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | THEM6, SLC30A6, SOD1 | NPC1 3030/4885ALDH1A1 1766/4885RAB9A 3790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.