Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL4643441

O=S(=O)([O-])C(F)(F)F.c1ccc(Cc2ccc([S+](c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.42

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
GPR3 P46089 1/20 0.40
CALM1 P0DP23 1/20 0.39
LMNA P02545 1/20 0.39
KCNH2 Q12809 6/20 0.36
PDPK1 O15530 1/20 0.36
FAAH O00519 1/20 0.35
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35
ELANE P08246 1/20 0.35
PRTN3 P24158 1/20 0.35
PRSS3 P35030 1/20 0.35
PLA2G10 O15496 1/20 0.35
PLA2G2A P14555 1/20 0.35
PTPN1 P18031 1/20 0.33
MMP13 P45452 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL4641374 0.90 GPR3 (0.36) CA2CA12CA1CA9CA14
Trifluoromethanesulfonic Acid SCHEMBL4643970 0.89 GPR3 (0.35) CA2CA12CA1CA9CA14
Trifluoromethanesulfonic Acid SCHEMBL6118365 0.88 GPR3 (0.48) CA2CA1CA9GPR3KCNH2
Trifluoromethanesulfonic Acid SCHEMBL31155703 0.86 GPR3 (0.50) CA2CA1CA9GPR3KCNH2
Trifluoromethanesulfonic Acid SCHEMBL37032 0.86 GPR3 (0.50) CA2CA1CA9GPR3KCNH2
Trifluoromethanesulfonic Acid SCHEMBL3190738 0.86 KCNH2 (0.40) CA2GPR3KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL10008137 0.84 GPR3 (0.48) CA2CA1CA9GPR3KCNH2
Trifluoromethanesulfonic Acid SCHEMBL9985275 0.83 TDP1 (0.43) CA2CA12CA1CA9CA14
SCHEMBL7738148 0.83 CA1 (0.51) CA2CA12CA1CA9CA14
Trifluoromethanesulfonic Acid SCHEMBL710435 0.82 ALDH1A1 (0.40) GPR3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1443042-B1 HYBRID ONIUM SALT WAKO PURE CHEM IND LTD (JP) 2008-08-13 EP disclosed
US-7101918-B2 Hybrid type onium salt WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2006-09-05 US disclosed
US-20050020710-A1 Hybrid onium salt WAKO PURE CHEMICALS INDUSTRIES, LTD. (JP) 2005-01-27 US disclosed
EP-1443042-A1 HYBRID ONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2004-08-04 EP disclosed