SCHEMBL4643575

SCHEMBL4643575

[CH2]CCC(=O)O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
ABL1 P00519 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 2/20 0.31
POLB P06746 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4647018 0.91 PRSS1 (0.34) CYP2C19HIF1AABL1ALDH1A1HSD17B10
SCHEMBL6546547 0.90 CYP2C19 (0.35) CYP2C19HIF1AABL1MAPTTDP1
SCHEMBL4647513 0.87 CYP2C19 (0.33) CYP2C19HIF1AABL1MAPTTDP1
SCHEMBL6545076 0.87 KDM4E (0.36) CYP2C19HIF1AABL1MAPTTDP1
SCHEMBL6656947 0.86 NR4A2 (0.38) CYP2C19HIF1AALDH1A1
SCHEMBL4644661 0.86 CYP2C19 (0.33) CYP2C19HIF1AABL1MAPTTDP1
SCHEMBL4644075 0.84 HIF1A (0.32) CYP2C19HIF1AABL1MAPTTDP1
SCHEMBL6072557 0.83 ABL1 (0.35) CYP2C19HIF1AABL1MAPTPOLB
SCHEMBL4641522 0.83 KDM4E (0.34) MAPTALDH1A1
SCHEMBL6663589 0.83 TSHR (0.41) CYP2C19HIF1AMAPTALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed