SCHEMBL4643717

SCHEMBL4643717

[CH2]CCC(=O)O[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.35
MAPT P10636 3/20 0.32
PRSS1 P07477 2/20 0.32
CTSG P08311 1/20 0.32
CTRB1 P17538 1/20 0.32
CMA1 P23946 1/20 0.32
L3MBTL1 Q9Y468 3/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPK1 P28482 2/20 0.32
KEAP1 Q14145 1/20 0.31
CYP19A1 P11511 1/20 0.31
PAM P19021 1/20 0.31
LMNA P02545 2/20 0.31
ALOX15 P16050 1/20 0.31
NR4A2 P43354 1/20 0.31
PKM P14618 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644017 0.89 PRSS1 (0.38) TDP1MAPTPRSS1L3MBTL1ALDH1A1
SCHEMBL4644249 0.85 ALDH1A1 (0.33) TDP1MAPTL3MBTL1ALDH1A1MAPK1
SCHEMBL4643834 0.83 TDP1 (0.36) TDP1MAPTPRSS1CTSGCTRB1
SCHEMBL4645473 0.82 L3MBTL1 (0.35) TDP1L3MBTL1ALDH1A1LMNASMN1; SMN2
SCHEMBL6555267 0.81 ALDH1A1 (0.35) TDP1MAPTPRSS1CTSGCTRB1
SCHEMBL3785120 0.81 ALDH1A1 (0.38) TDP1MAPTALDH1A1MAPK1LMNA
SCHEMBL4642474 0.80 MAPT (0.38) TDP1MAPTPRSS1L3MBTL1ALDH1A1
SCHEMBL4642622 0.79 ALDH1A1 (0.37) TDP1MAPTL3MBTL1ALDH1A1MAPK1
SCHEMBL4644427 0.79 GPR84 (0.36) TDP1MAPTPRSS1L3MBTL1ALDH1A1
SCHEMBL28063157 0.79 KDM4E (0.50) TDP1L3MBTL1ALDH1A1MAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed