SCHEMBL4644068

SCHEMBL4644068

O=Cc1ccccc1OC(=O)CCCCCl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.51
HPGD P15428 3/20 0.51
HTT P42858 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
PTGDR2 Q9Y5Y4 1/20 0.51
KMT2A Q03164 6/20 0.45
MEN1 O00255 3/20 0.43
KDM4E B2RXH2 2/20 0.43
RECQL P46063 2/20 0.43
SRC P12931 2/20 0.42
RAD52 P43351 1/20 0.41
LMNA P02545 3/20 0.41
GAA P10253 1/20 0.41
NPC1 O15118 1/20 0.39
NFKB1 P19838 1/20 0.39
RAB9A P51151 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642152 0.95 ALDH1A1 (0.53) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL4644146 0.89 ALDH1A1 (0.52) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL4644325 0.86 PTGDR2 (0.49) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL2763300 0.86 PTGDR2 (0.49) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL7285448 0.84 KMT2A (0.57) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL2763392 0.84 PTGDR2 (0.47) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL2762750 0.84 ALDH1A1 (0.50) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL4643449 0.84 ALDH1A1 (0.50) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL20143639 0.83 KMT2A (0.63) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL4642017 0.83 PTGDR2 (0.49) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed