Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.40 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.40 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.40 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2763300 | 0.98 | PTGDR2 (0.49) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL2762750 | 0.94 | ALDH1A1 (0.50) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL4644325 | 0.86 | PTGDR2 (0.49) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL4644068 | 0.84 | ALDH1A1 (0.51) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL7285448 | 0.84 | KMT2A (0.57) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL4643449 | 0.84 | ALDH1A1 (0.50) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL20143639 | 0.83 | KMT2A (0.63) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL4642017 | 0.83 | PTGDR2 (0.49) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL4642152 | 0.83 | ALDH1A1 (0.53) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL18803118 | 0.82 | KDM4E (0.67) | PTGDR2ALDH1A1HPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951653-B1 | SALICYLIC ACID DERIVATIVES | NICOX SA (FR) | 2010-10-20 | — | — | EP | disclosed |
| US-20080293781-A1 | Salicylic Acid Derivatives | NICOX S.A. (FR) | 2008-11-27 | — | — | US | disclosed |
| EP-1951653-A1 | SALICYLIC ACID DERIVATIVES | NicOx S.A. (FR) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007060112-A1 | SALICYLIC ACID DERIVATIVES | NICOX S.A. (FR) | 2007-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293781-A1 | Salicylic Acid Derivatives | PTGS2, PTGS1, PTGES2 | PTGDR2 98/4885ALDH1A1 51/4885HPGD 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.