SCHEMBL4644355

SCHEMBL4644355

CC(=O)O[SiH](C(C)C)C(C)C

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.41
ALDH1A1 P00352 3/20 0.35
TDP1 Q9NUW8 1/20 0.35
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM1 P11229 1/20 0.31
TBXA2R P21731 1/20 0.31
GALR3 O60755 1/20 0.30
MAPT P10636 1/20 0.30
BLM P54132 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL703630 0.77 TSHR (0.41) TSHRALDH1A1CHRM2CHRM4CHRM1
SCHEMBL23092978 0.74
SCHEMBL7758856 0.70 ALOX15 (0.35) ALDH1A1TDP1
SCHEMBL4644764 0.70 TSHR (0.32) TSHRALDH1A1TDP1
SCHEMBL13318279 0.69 ALDH1A1 (0.35) TSHRALDH1A1TDP1CHRM2CHRM4
SCHEMBL203518 0.67 ALDH1A1 (0.44) TSHRALDH1A1TDP1BLM
SCHEMBL2771869 0.67 ALDH1A1 (0.44) TSHRALDH1A1TDP1BLM
SCHEMBL27885882 0.67 TSHR (0.33) TSHR
SCHEMBL4302725 0.67 TSHR (0.43) TSHRALDH1A1CHRM2CHRM4CHRM1
SCHEMBL2363424 0.65 TSHR (0.42) TSHRALDH1A1CHRM2CHRM4CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed
EP-1085022-A1 A method of manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via Si-C- bonds Dow Corning Asia, Ltd. (JP) 2001-03-21 EP disclosed
US-6060620-A Method for manufacturing an acyloxysilane compound having functional groups bonded to silicon atoms via SI--C bonds DOW CORNING ASIA, LTD. (JP) 2000-05-09 US disclosed