SCHEMBL4644764

SCHEMBL4644764

CC(C)[SiH](OC(=O)CO)C(C)C

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 2/20 0.31
ALDH1A1 P00352 1/20 0.31
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP3 P08254 1/20 0.30
MMP9 P14780 1/20 0.30
MMP13 P45452 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4647651 0.81 CA1 (0.30) CA1
SCHEMBL7758856 0.80 ALOX15 (0.35) TDP1ALDH1A1MMP1MMP2MMP3
SCHEMBL4645686 0.78 TSHR (0.31) TSHRCA1
SCHEMBL7761299 0.76 ALDH1A1 (0.48) TSHRALDH1A1CA1
SCHEMBL4645531 0.75
SCHEMBL4644680 0.72 LMNA (0.33) TSHR
SCHEMBL4642473 0.72 LMNA (0.33) TSHR
SCHEMBL4644355 0.70 TSHR (0.41) TSHRTDP1ALDH1A1
SCHEMBL4641933 0.70 LMNA (0.36) TSHR
SCHEMBL4644349 0.69 TSHR (0.30) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed