Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.46 |
| ▸ | WNT3A | P56704 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28189021 | 0.89 | MEN1 (0.51) | CTSDNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL27875398 | 0.88 | CTSD (0.54) | CTSDNPC1RAB9AESR1ESR2 | |
| SCHEMBL2891858 | 0.88 | MEN1 (0.50) | CTSDNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL27995993 | 0.86 | POLB (0.52) | NPC1RAB9AALDH1A1HPGDHTT | |
| SCHEMBL28280045 | 0.86 | TAS1R3 (0.53) | CTSDESR1ESR2ALDH1A1HPGD | |
| SCHEMBL7257515 | 0.86 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1KMT2AHSD17B10LMNA | |
| SCHEMBL27600938 | 0.85 | KAT6A (0.42) | CTSDNPC1RAB9AESR1ESR2 | |
| SCHEMBL28026700 | 0.84 | KMT2A (0.51) | ALDH1A1HTTMAPTNPSR1L3MBTL1 | |
| SCHEMBL28990208 | 0.83 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1KMT2AHSD17B10LMNA | |
| SCHEMBL28026711 | 0.83 | IRAK4 (0.54) | ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116180458-A | Medical geothermal carpet fabric and preparation method thereof | 江苏省华强纺织有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-109369592-A | A kind of synthetic method of sweet orange flavones | 陕西嘉禾生物科技股份有限公司 | 2019-02-22 | — | — | CN | claimed |
| CN-109020940-A | A kind of synthetic method of scutellarin | 陕西嘉禾生物科技股份有限公司 | 2018-12-18 | — | — | CN | claimed |
| CN-107876092-A | The high stability titanium catalyst of ester exchange carbonate synthesis benzene methyl and diphenyl carbonate | 华东理工大学 | 2018-04-06 | — | — | CN | claimed |
| CN-107417719-A | A kind of titanium chelate catalyst for being used for carbonate synthesis benzene methyl and diphenyl carbonate | 华东理工大学 | 2017-12-01 | — | — | CN | claimed |
| CN-105523874-A | Preparation method of 2,2-dihalo-1,3-dicarbonyl derivatives | ZHANGJIAGANG INST IND TECHNOLOGIES SOOCHOW UNIV | 2016-04-27 | — | — | CN | claimed |
| CN-105503635-A | Preparation method for 2-amidoformyl-1,3-dicarbonyl derivative | UNIV SOOCHOW | 2016-04-20 | — | — | CN | claimed |
| CN-105461496-A | Preparation method for 2-halogenated-1,3-dicarbonyl derivative | CHINASUN SPECIALTY PRODUCTS CO LTD | 2016-04-06 | — | — | CN | claimed |
| CN-101463030-A | Method for preparing anethol trithione | FUJIAN SHENNA BIOENGINEERING C (CN) | 2009-06-24 | — | — | CN | claimed |
| CN-109942523-B | Benzofuran and benzofuran coumarin derivatives, and preparation method and application thereof | 华东师范大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-105646425-B | A kind of preparation method of acacetin | 上海医药工业研究院 | 2019-05-14 | — | — | CN | disclosed |
| CN-109651325-A | Synthetic method of naphtho [1,2,3-de ] benzopyran-2, 7-diketone compound | 青岛理工大学 | 2019-04-19 | — | — | CN | disclosed |
| CN-109020940-A | A kind of synthetic method of scutellarin | 陕西嘉禾生物科技股份有限公司 | 2018-12-18 | — | — | CN | disclosed |
| CN-109020940-A | A kind of synthetic method of scutellarin | 陕西嘉禾生物科技股份有限公司 | 2018-12-18 | — | — | CN | disclosed |
| CN-101463030-A | Method for preparing anethol trithione | FUJIAN SHENNA BIOENGINEERING C (CN) | 2009-06-24 | — | — | CN | disclosed |
| US-20080287474-A1 | Antiproliferative Pyrimidyl, Fused Pyrimidyl and Pyrimidyl Hydrazones | LABORATOIRES SERONO SA (CH) | 2008-11-20 | — | — | US | disclosed |
| EP-1957469-A1 | ANTIPROLIFERATIVE PYRIMIDYL, FUSED PYRIMIDYL AND PYRIMIDYL HYDRAZONES | Laboratoires Serono SA (CH) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007065940-A1 | ANTIPROLIFERATIVE PYRIMIDYL, FUSED PYRIMIDYL AND PYRIMIDYL HYDRAZONES | LABORATOIRES SERONO S.A. (CH) | 2007-06-14 | — | — | WO | disclosed |
| CN-1252069-C | 2-aryl-naphthyridin-4-ones as antitumor agents | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2006-04-19 | — | — | CN | disclosed |
| CN-1259947-A | 2-aryl-naphthyridin-4-ones as antitumor agents | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2000-07-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287474-A1 | Antiproliferative Pyrimidyl, Fused Pyrimidyl and Pyrimidyl Hydrazones | TYMP, DHFR, DPYD | CTSD 4406/4885NPC1 2298/4885RAB9A 3387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.