SCHEMBL4644571

SCHEMBL4644571

C=C(C)C(=O)OCC(=O)O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
TSHR P16473 1/20 0.32
ATM Q13315 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2184635 0.85 ELANE (0.41) ELANETDP1POLBAPEX1HTT
SCHEMBL6072557 0.81 ABL1 (0.35) POLBHTTMAPTTSHR
SCHEMBL24312528 0.80 THRB (0.41) ELANETDP1POLBAPEX1HTT
SCHEMBL4647513 0.78 CYP2C19 (0.33) TDP1HTTALDH1A1MAPTTSHR
SCHEMBL5974108 0.78 ATM (0.32) TDP1HTTALDH1A1MAPTATM
SCHEMBL6546547 0.78 CYP2C19 (0.35) TDP1POLBALDH1A1MAPTTSHR
SCHEMBL24312510 0.77 HTT (0.44) ELANETDP1POLBAPEX1HTT
SCHEMBL24312363 0.77 TDP1 (0.47) ELANETDP1POLBAPEX1HTT
SCHEMBL24312808 0.76 TDP1 (0.49) TDP1POLBAPEX1HTTALDH1A1
SCHEMBL27754290 0.76 ALDH1A1 (0.34) ELANETDP1POLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed