SCHEMBL4644746

SCHEMBL4644746

CC[CH]C(=O)OC(=O)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.31
FAAH O00519 8/20 0.31
CES2 O00748 3/20 0.31
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4643771 0.83 FAAH (0.34) CES1FAAHCES2MEN1CYP1A2
SCHEMBL4641872 0.82 PRKCA (0.31)
SCHEMBL4643420 0.80
SCHEMBL4647254 0.80
SCHEMBL4641581 0.76
SCHEMBL6889394 0.75 KEAP1 (0.35)
SCHEMBL3171987 0.75 KEAP1 (0.35)
SCHEMBL15347632 0.75 HCAR2 (0.53)
SCHEMBL4485811 0.73 ALDH1A1 (0.36) CES1FAAHCES2MEN1CYP1A2
SCHEMBL28106406 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed