Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27251960 | 0.88 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRCYP3A4TDP1 | |
| SCHEMBL10887099 | 0.88 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRCYP3A4TDP1 | |
| Nitrosobenzene SCHEMBL3176061 | 0.82 | — | — | |
| Nitrosobenzene SCHEMBL103117 | 0.82 | — | — | |
| Nitrosobenzene SCHEMBL28014686 | 0.82 | ALDH1A1 (0.59) | ALDH1A1HSD17B10TSHRCYP3A4TDP1 | |
| SCHEMBL14639889 | 0.80 | HTT (0.40) | ALDH1A1HSD17B10TSHRCYP3A4TDP1 | |
| SCHEMBL27251980 | 0.80 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TSHRCYP3A4TDP1 | |
| SCHEMBL27251974 | 0.80 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TSHRCYP3A4TDP1 | |
| Nitrosobenzene SCHEMBL30901881 | 0.79 | — | — | |
| Nitrosobenzene SCHEMBL27874353 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070783-A1 | RADIATION-SENSITIVE RESIN COMPOSITION, POLYMER, AND METHOD FOR FORMING RESIST PATTERN | JSR CORPORATION (JP) | 2012-03-22 | — | — | US | disclosed |
| US-20120065291-A1 | RADIATION-SENSITIVE RESIN COMPOSITION, POLYMER, AND COMPOUND | JSR CORPORATION (JP) | 2012-03-15 | — | — | US | disclosed |
| US-20080076924-A1 | Piperazines as P2X7 antagonists | ABBOTT LABORATORIES | 2008-03-27 | — | — | US | disclosed |
| US-20080076924-A1 | Piperazines as P2X7 antagonists | ABBOTT LABORATORIES | 2008-03-27 | — | — | US | disclosed |
| US-7244845-B2 | Process for preparing cyclic N-substituted alpha-imino carboxylic acids | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-07-17 | — | — | US | disclosed |
| US-7244845-B2 | Process for preparing cyclic N-substituted alpha-imino carboxylic acids | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-07-17 | — | — | US | disclosed |
| EP-0009267-A1 | Process for the preparation of p-nitroso-diphenylhydroxylamines | AKZO N.V. (NL) | 1980-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076924-A1 | Piperazines as P2X7 antagonists | P2RX7, P2RX1, P2RX2 | ALDH1A1 852/4885HSD17B10 4228/4885TSHR 2283/4885 |
| US-20120065291-A1 | RADIATION-SENSITIVE RESIN COMPOSITION, POLYMER, AND COMPOUND | RAD51, RER1, XRCC5 | ALDH1A1 2935/4885HSD17B10 4462/4885TSHR 3647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.