Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL464532 | 0.80 | ALDH1A1 (0.56) | HTTALDH1A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL12922924 | 0.76 | ESR1 (0.68) | ALDH1A1CYP3A4TDP1ACMSDMEN1 | |
| SCHEMBL2838545 | 0.76 | ALDH1A1 (0.56) | ALDH1A1CYP3A4HSD17B10TDP1ACP3 | |
| SCHEMBL13179896 | 0.74 | MAOA (0.44) | HTTALDH1A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL23527429 | 0.73 | CHRNB2 (0.58) | ALDH1A1CYP3A4HSD17B10TDP1ACP3 | |
| SCHEMBL27251974 | 0.73 | ALDH1A1 (0.44) | HTTALDH1A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL27251980 | 0.73 | ALDH1A1 (0.44) | HTTALDH1A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL4624505 | 0.72 | SLC6A2 (0.46) | HTTALDH1A1KMOMEN1KMT2A | |
| SCHEMBL13376242 | 0.72 | PGR (0.45) | NPC1MAPT | |
| SCHEMBL27259386 | 0.72 | ESR1 (0.52) | HTTALDH1A1CYP3A4TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1739485-A1 | RESIST COMPOSITION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-01-03 | — | — | EP | disclosed |