Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4689320 | 0.86 | TRPV1 (0.60) | NPC1RAB9AEPHX2ALDH1A1HTT | |
| SCHEMBL15442351 | 0.85 | ALDH1A1 (0.60) | RAB9AMAOBALDH1A1CA12CA1 | |
| SCHEMBL15442352 | 0.85 | ALDH1A1 (0.60) | RAB9AMAOBALDH1A1CA12CA1 | |
| SCHEMBL4648073 | 0.85 | MAPT (0.56) | TGM2NPC1RAB9AMAOBALDH1A1 | |
| SCHEMBL9277123 | 0.85 | MAPT (0.56) | TGM2NPC1RAB9AMAOBALDH1A1 | |
| SCHEMBL3986444 | 0.85 | MAPT (0.56) | TGM2NPC1RAB9AMAOBALDH1A1 | |
| SCHEMBL4647289 | 0.84 | MMP1 (0.61) | TGM2NPC1RAB9AMAOBALDH1A1 | |
| SCHEMBL3040573 | 0.82 | ALDH1A1 (0.64) | NPC1RAB9AMAOBALDH1A1HTT | |
| SCHEMBL4646465 | 0.81 | MAOA (0.51) | TGM2NPC1RAB9AMAOBALDH1A1 | |
| SCHEMBL3035626 | 0.81 | MMP1 (0.61) | TGM2NPC1RAB9AMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |