Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPP5A | Q14642 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3049709 | 0.70 | — | — | |
| SCHEMBL4646421 | 0.68 | KDM1A (0.34) | — | |
| SCHEMBL13726548 | 0.65 | INPP5A (0.37) | INPP5A | |
| SCHEMBL14323215 | 0.64 | — | — | |
| SCHEMBL9623360 | 0.61 | CHRM5 (0.36) | INPP5A | |
| SCHEMBL7414222 | 0.61 | HSD11B1 (0.35) | — | |
| SCHEMBL4255696 | 0.61 | — | — | |
| SCHEMBL3378135 | 0.59 | SLC6A9 (0.37) | — | |
| SCHEMBL24868172 | 0.59 | KDM1A (0.31) | — | |
| SCHEMBL24230116 | 0.59 | HSD11B1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960360-A1 | AZETIDINE DERIVATIVES AS GLYT1 INHIBITORS | MERCK SHARP & DOHME LTD. (GB) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007060484-A1 | AZETIDINE DERIVATIVES AS GLYT1 INHIBITORS | MERCK SHARP & DOHME LIMITED (GB) | 2007-05-31 | — | — | WO | disclosed |